早期联合应用倍他乐克和果糖二磷酸钠对急性心肌梗死溶栓治疗患者临床疗效观察
投稿时间:2009-06-22    点此下载全文
引用本文:冯润川、谢丽圣、潘华、陈富荣.早期联合应用倍他乐克和果糖二磷酸钠对急性心肌梗死溶栓治疗患者临床疗效观察[J].医学研究杂志,2010,39(1):77-79
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冯润川、谢丽圣、潘华、陈富荣 广西壮族自治区南宁市第四人民医院内一科(冯润川、潘华、陈富荣)广西壮族自治区南宁市第二人民医院老年科(谢丽圣) 
中文摘要:目的探讨早期联合应用倍他乐克(酒石酸美托洛尔片)和果糖二磷酸钠对急性心肌梗死溶栓治疗患者的临床疗效。方法对84例急性心肌梗死且符合溶栓治疗指征患者,随机分为加倍他乐克和果糖二磷酸钠溶栓前治疗组(48例)和对照组(36例),观察两组患者溶栓后再灌注心律失常(RA)的发生及早期临床症状、体征、心肌损伤恢复情况,了解其对急性心肌梗死溶栓治疗患者临床作用。结果治疗组RA发生率为36.1%,对照组RA发生率为71.4%,两组差异有显著性(P<0.05);治疗组胸痛、心悸症状发生率减少,心肌酶谱恢复较对照组快,两组差异有显著性(P<0.05)。 结论早期联合应用倍他乐克和果糖二磷酸钠对急性心肌梗死溶栓治疗患者再灌注心律失常有明显的抑制作用,减轻梗死后临床症状及心肌损伤。
中文关键词:急性心肌梗死、再灌注心律失常、临床疗效、酒石酸美托洛尔片、果糖二磷酸钠注射液
 
Clinical Effect of Metoprolol Tartrate Tablets and Sodium Fructose Diphosphate Injection in Acute Myocardial Infarction Patients with Thrombolytic Therapy
Abstract:ObjectiveTo investigate the clinical effects of Metoprolol Tartrate Tablets and Sodium Fructose Diphosphate(FDP) :injection in the early treatment of 48 cases of acute myocardial infarction(AMI) patients with thrombolytic therapy.Methods84 cases of acute myocardial infarction who were in accordance with the indications for thrombolytic therapy in patients were randomly divided into a treatment group(group A,48 cases, treated with Metoprolol Tartrate Tablets and Sodium Fructose Diphosphate Injection) and a control group(group B,36 cases, treated with the conventional therapy).The occurrence of reperfusion arrhythmias,early sighs and symptms,and retoration of myocardial injury were observed in patients after thrombolytic therapy in order to understand clinical effect on the patients with that treatment.ResultsIn treatment group there were decreased incidence of heart symptoms (chest pain, cardiopalmus) and RA(group A,36.1%;group B,71.4%),improved recovery of cardiac muscde enzymogram as compared to control,which was significantly different with control and between treatment groups (P<0.05).ConclusionEarly combination of metoprolol and FDP of thrombolytic therapy in acute myocardial infarction patients with reperfusion arrhythmias has significantly inhibiting effect,with reducing the clinical symptoms of infarction and myocardial injury.
keywords:Acute myocardial infarction  Reperfusion arrhythmias  Clinical effect  Metoprolol tartrate tablets  Sodium fructose diphosphate injection
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