胆汁反流性胃炎临床研究与分析
投稿时间:2009-09-27    点此下载全文
引用本文:王滨、孙天燕、王晓宇、李宏、吴作艳.胆汁反流性胃炎临床研究与分析[J].医学研究杂志,2010,39(1):96-98
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王滨、孙天燕、王晓宇、李宏、吴作艳 首都医科大学附属北京安贞医院ICU(王滨) 北京市第六医院(孙天燕、王晓宇、李宏、吴作艳) 
中文摘要:目的探讨胆汁反流性胃炎(残胃除外)的临床特点。方法对1328例胆汁反流性胃炎(残胃除外)进行临床观察,随机按年龄组筛选425例单纯浅表性胃炎作为对照,所有患者均进行了胃黏膜幽门螺杆菌(Hp)快速尿素酶检测。其中观察组664例及所有对照组行腹部B超检查观察胆囊病变。结果1328例中,男性797例,女性531例,男/女≈1.5/1。胆汁反流性胃炎的检出率随着年龄升高而下降。其中单纯胆汁反流性胃炎651例(49%);合并胃溃疡86例(6.5%);合并十二指肠球部溃疡412例(31%);合并复合性溃疡122例(9.2%);合并其他57例(4.3%)。观察组中Hp(+)298例(22.44%),对照组中Hp(+)147例(33.65%),明显高于观察组。观察组中胆囊疾患的检出率为221例(33.3%),高于对照组的72例(16.9%)。结论不论男女,胆汁反流性胃炎的检出率随着年龄升高而下降;胆汁反流性胃炎患者多合并有溃疡;胆汁反流性胃炎患者合并胆囊疾患者较高;胆汁反流性胃炎的Hp感染率明显低于非胆汁反流性胃炎。
中文关键词:胆汁反流性胃炎、幽门螺杆菌、胆囊疾患
 
Clinic Study and Analysis of Bile Reflux Gastritis
Abstract:ObjectiveTo explore the clinical character istics of bile reflux gastritis. MethodsWe observed 1328 patients with bile reflux gastritis(excluding gastritis of the remnant stomach),and selected 425 superficial gastritis as control group.All the patients took helicobacter pylori(Hp) rapid urease examination. 664 cases in observed group and all in patients of control group were examined for bile disease by UB. ResultsIn 1328 patients, there were 797 male and 531 female,and the ratio of male and female was 1.5/1.The detecting rate of bile reflux gastritis was decreased along with aging. Among all the patients, there were 651 simple superficial gastritis(49%), 86 gastric ulcer(6.5%), 412 duodenal ulcer (31%), 122 combined ulcer(9.2%) and 57 other disease(4.7%).In observed group,1030 HP(77.56%) were regative; 298 Hp(22.44%) were positive, and in control group, 282 Hp(66.35%) were regative,147 Hp(33.65%) were positive.The amount of gallbladder disease resection was 221(33.3%), which was more than that of control group(169%). ConclusionThe detecting rate of bile reflux gastritis was decreased along with aging.Bile reflux gastritis is more often combined with ulcer disease or gallbladder disease. The Hp infection rate of bile reflux gastritis is significant lower than that of non-bile reflux gastritis.
keywords:Bile reflux gastritis  Helicobacter pylori  Gallbladder disease
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