180例健康人血浆神经肽Y相关因素的逐步回归分析
投稿时间:2009-06-09  修订日期:2010-01-04  点此下载全文
引用本文:齐云萍、邓洁、马佳、王南.180例健康人血浆神经肽Y相关因素的逐步回归分析[J].医学研究杂志,2010,39(1):98-100
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齐云萍、邓洁、马佳、王南 云南省昆明市延安医院干部科干三病区 
中文摘要:目的采用逐步回归分析180例健康人血浆神经肽Y因素进行探讨。方法通过放射免疫法进行测量血浆神经肽Y,同时通过心脏彩色超声测定右室舒张末期内径(RVDD)、室间隔舒张末期厚度(IVSd)、左室舒张末期内径(LVIDd)、左室后壁舒张末期厚度(LVPWd)、左室射血分数(EF)、左室每搏心排出量(SV)、心排出量(CO)、心指数(CI)和每搏指数(SI)。此外,还测定每个研究对象的身高、体重、血压、心率、皮下脂肪厚度等。结果不同性别和年龄的血浆神经肽Y无显著性差异(P≥005),健康人血浆神经肽Y的分布呈正态分布,95%正常值范围为70.27~190.61,99%正常值范围为51.23~209.65。结论血浆神经肽Y的主要相关因素是EF、体重、IVSD、舒张压、CO、SV和腹壁脂肪EF和体重与血浆神经肽Y呈负相关,其余5个因素与血浆神经肽Y呈正相关。
中文关键词:健康人、神经肽Y、正常值范围
 
The Stepwise Regression Analysis of the Related Factors with Plasma Neuropeptide Y in 180 Healthy People
Abstract:ObjectiveTo explore the related factors with plasma neuropeptide Y in 180 normal healthy people by stepwise regression analysis. MethodsRight ventricular end-diastolic diameter(RVDD), inter-ventricular septum end-diastolic thickness(IVST), left ventricular end-diastolic diameter(LVDD), left ventricular posterior wall end-diastolic thickness(LVPWT), ejection fraction(EF), strole volume(SV), cardiac output(CO), cadiac output index(CI), stroke volume index(SI) and plasma neuropeptide Y were measured respectively by echocardiography and immunoradioassay in all subjects. In addition, we examined the height,weight,blood pressure,heart rate and subcutaneous fat thickness in every subjects. ResultsThe plasma neuropeptide Y wasn’t significant difference in different gender and age(P≥0.05). The plasma neuropeptide Y of healthy population was normal distribution and the 95% of confidence interval 70.27 to 190.61,and 99% of confidence interval was 51.23 to 209.65. ConclusionThe EF,height,LVST,diastolic blood pressure,CO,SV and subcutaneous fat thickness were the major related-factors of neuropeptide Y in plasma. The EF and height were negatively correlated with plasma neuropeptide Y,and other five factors were postive correlated with it.
keywords:Healthy population  Neuropeptide Y  Related-factors
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