| 帕瑞昔布钠用于泌尿外科腹腔镜术后镇痛效果的观察 |
| 投稿时间：2009-10-26 修订日期：2009-12-25 点此下载全文 |
| 引用本文：吴浩,蒋忠,马正良.帕瑞昔布钠用于泌尿外科腹腔镜术后镇痛效果的观察[J].医学研究杂志,2010,39(3):109-110 |
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| 中文摘要:摘要目的观察帕瑞昔布钠用于泌尿外科腹腔镜术后镇痛的效果及不良反应。方法40例ASAⅠ~Ⅲ级的患者行择期泌尿外科腹腔镜手术，随机分为两组：氟比洛芬酯组（Ⅰ组，n=20）：手术结束后2h静脉给予氟比洛芬酯100mg，随后100mg/12h持续3天；帕瑞昔布钠组（Ⅱ组，n=20）：手术结束后2h静脉给予帕瑞昔布钠40mg，随后40mg/12h持续3天。观察两组术后2h、4h、16h、24h、48h的VAS评分及恶心、呕吐等不良反应的发生率。结果两组患者术后2h的VAS评分平均值在4～5分之间，其他时间点在0～3分的范围。两组术后VAS评分的差异无统计学意义。结论帕瑞昔布钠可以有效缓解中等程度的术后疼痛且不良反应的发生率低，是泌尿外科腹腔镜手术较为理想的术后镇痛药物。 |
| 中文关键词:帕瑞昔布钠 氟比洛芬酯 镇痛 泌尿外科手术 腹腔镜 |
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| The Postoperative Analgesic Effects of Parecoxib for Laparoscopic Urological Surgery |
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| Abstract:AbstractObjectiveTo evaluate the postoperative analgesic effects of parecoxib for laparoscopic urological surgery. MethodsForty patients with ASA scale ofⅠto Ⅲ underwent laparoscopic urological surgery were randomly divided into two groups: the flurbiprofen group (group Ⅰ, n=20) with IV flurbiprofen 100 mg at 2 hours after operation, and 100 mg twice a day during 3 days after operation; and the parecoxib group (group Ⅱ, n=20）with IV parecoxib 40 mg at 2 hours after operation, and 40 mg twice a day during 3 days after operation. The VAS score at 2,4,16,24 and 48 hours after operation and the adverse effects were recorded. ResultsThe average VAS score of the two groups was 4 to 5 at 2 hours after operation, and was 0~3 at other time points. There was no significant difference among two groups in the VAS score. ConclusionParecoxib can provid effective postoperative analgesia for patients underwent laparoscopic urological surgery as flurbiprofen. |
| keywords:Parecoxib Flurbiprofen Analgesia Urological surgery Laparoscope |
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