| C反应蛋白与扩张型心肌病伴不同类型心房纤颤的关系研究 |
| 投稿时间：2009-12-08 修订日期：2009-12-22 点此下载全文 |
| 引用本文：邓伟,唐其柱,周恒,郭海鹏.C反应蛋白与扩张型心肌病伴不同类型心房纤颤的关系研究[J].医学研究杂志,2010,39(4):26-28 |
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| 基金项目:国家博士学科点专项科研基金资助项目(20070486103) |
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| 中文摘要:目的探讨扩张型心肌病(DCM)所伴心房纤颤及心房纤颤类型是否和炎症相关。方法观察118例单纯或伴心房纤颤DCM患者左心房内径(LAD)、左心室射血分数（LVEF）、左心室舒张末内径（LVEDD）及高敏C反应蛋白（hs-CRP）水平。结果Hs-CRP水平在DCM伴阵发性心房纤颤组及持续性心房纤颤组较单纯DCM组明显升高［（5.35±2.16）mg/L vs (2.97±1.65) mg/L,P<0.01;(7.43±2.46)mg/L vs (2.97±1.65)mg/L,P<0.01］，伴持续性心房纤颤组hs-CRP水平高于伴阵发性心房纤颤组［（7.43±2.46）mg/L vs (5.35±2.16) mg/L,P<0.01］；初发心房纤颤和既往有心房纤颤病史患者hs-CRP水平没有明显差异（P>0.05）。结论单纯DCM、DCM伴阵发性心房纤颤、DCM伴持续性心房纤颤hs-CRP水平逐渐升高，炎症参与了DCM所伴心房纤颤的形成和维持。 |
| 中文关键词:C反应蛋白 扩张型心肌病 心房纤颤 |
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| A Study on the Relationship between C Reactive Protein and Dilated Cardiomyopathy with Different Types of Atrial Fibrillation |
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| Abstract:AbstractObjectiveThis study was designed to evaluate the correlation between different types of atrial fibrillation in DCM patients and inflammation.MethodsThe levels of LAD,LVEF,LVEDD and hs-CRP in 108 DCM patients with or without atrial fibrillation were observed.ResultsHs-CRP was higher in the DCM with paroxysmal or persistent atrial fibrillation group than in the DCM without atrial fibrillation group (5.35±2.16mg/L vs 2.97±1.65mg/L,P<0.01; 7.43±2.46mg/L vs 2.97±1.65mg/L,P<0.01）; hs-CRP was higher in the DCM with persistent atrial fibrillation group than in the DCM with paroxysmal atrial fibrillation group（7.43±246mg/L vs 5.35±216mg/L,P<0.01）.There was no significant difference in hs-CRP level among the DCM with different history of atrial fibrillation groups (P>0.05).ConclusionHs-CRP level gradually elevated in DCM without atrial fibrillation,with paroxysmal and persistent atrial fibrillation patients.Inflammation was related to initiation and maintenance of atrial fibrillation in DCM patients. |
| keywords:C-reactive protein Dilated cardiomyopathy Atrial fibrillation |
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