| 系统性红斑狼疮中EB病毒感染研究 |
| 投稿时间：2009-12-28 修订日期：2010-03-12 点此下载全文 |
| 引用本文：史振军,王涛,刘跃华,曹鸿玮.系统性红斑狼疮中EB病毒感染研究[J].医学研究杂志,2010,39(5):56-57 |
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| 基金项目:河南省2004科技攻关计划项目(424410164) |
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| 中文摘要:目的了解系统性红斑狼疮（SLE）的发病与EB病毒(epstein-barr virus,EBV)感染的相关性。方法通过荧光定量PCR方法检测40名SLE患者和40名正常人EBV-DNA的表达。结果40名SLE患者中11例阳性；40名正常人对照组3例阳性，两组对比有显著差异性（P<0.05）。结论SLE患者EBV感染率高于正常人，EBV感染可能是SLE发生发展因素。 |
| 中文关键词:系统性红斑狼疮 Epstein-Barr病毒 PCR |
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| Study of Epstein-Barr Virus Infection in Systemic Lupus Erythematosus |
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| Abstract:ObjectiveTo investigate the relationship between systemic lupus erythematosus and Epstein-Barr virus infection. MethodsExpression of EBV-DNA was detected by fluorescent quantitative PCR assay in SLE patients (n=40) and normal control individuals (n=40). ResultsEBV-DNA in 11 were positive of the 40 patients and 3 were positive of the 40 normal control individual,and there was significant different（P<0.05）. ConclusionThe rate of EBV infection in SL E patients is higher than that in normal control individuals, and EBV infection might be an etiologic factor in SLE. |
| keywords:SLE EBV PCR |
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