| Abstract:ObjectiveTo investigate the effect of minimally invasive hematoma on clinical and serum levels of inflammatory cytokines in patients with hypertensive intracerebral hemorrhage. Methods60 patients with acute ICH and hypertension were randomly divided into two groups.All patients were given conventional treatment patients. In minimally invasive group,patients were treated with minimally invasive hematoma removal operation on the basis of conventional therapy.Before treatment and 7 days, 14 days after treatment, serum hs-CRP, IL-6, TNF-α contents of patients in two groups were tested, and the neurological deficit scores were evaluated. ResultsOn the 7 days, 14 days after treatment,the serum hs-CRP, IL-6, TNF-α content in the minimally invasive group were significantly lower than those in the control group (P<0.05,P<0.01).On the 14 days after treatment,the neurological function deficit score in the minimally invasive group was significantly lower than that in control group (P<0.01).The total effective rate of the minimally invasive group was significantly higher than that of control group (P<0.01). ConclusionThe serum hs-CRP, IL-6, TNF-α was increased in the acute stage of hypertensive cerebral hemorrhage,which indicated that they participated in the pathophysiological process of cerebral hemorrhage. Minimally invasive hematoma operation could reduce hs-CRP, IL-6, TNF-α levels and thus to improve the prognosis of cerebral hemorrhage. |
