| 采用咪达唑仑鼻黏膜镇静技术辅助儿童口腔治疗的临床研究 |
| 投稿时间：2010-02-28 修订日期：2010-04-06 点此下载全文 |
| 引用本文：万阔,马林,景泉,陈曦.采用咪达唑仑鼻黏膜镇静技术辅助儿童口腔治疗的临床研究[J].医学研究杂志,2010,39(6):36-38 |
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| 基金项目:美国中华医学会CMB基金(A350600) |
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| 中文摘要:目的评价咪达唑仑鼻黏膜给药镇静术用于儿童牙科治疗恐惧患者口腔治疗的临床效果。方法选取因恐惧不能配合口腔治疗的患儿，无镇静治疗禁忌且口腔治疗内容相对简单，采用0.4mg/kg咪达唑仑经鼻黏膜给药，镇静后再行口腔治疗，评价治疗中的安全性、治疗完成情况及总成功率。结果共16例患儿接受治疗，年龄47.53±12.52个月，体重1653±331kg，药物起效时间7.80±4.63min，Houpt治疗完成情况评分4.00±1.56分，总成功率81.25％，未出现严重不良反应。结论针对儿童患者简单短时的口腔治疗，采用咪达唑仑鼻黏膜镇静术安全有效。 |
| 中文关键词:鼻腔给药 镇静 咪达唑仑 儿童牙科治疗恐惧 |
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| he Application of Midazolam Intranasal Sedation in Simple Pedodontic Procedures |
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| Abstract:ObjectiveTo observe the sedation effect and safety of intranasal midazolam in simple pedodontic procedures. Methods In dental outpatient, intranasal midazolam by 0.4mg/kg dosage was administrated to healthy children with dental treatment fear whose oral procedures were relative simple. The Houpt score, success rate and side effect were recorded. Results16 pediatric patient were enrolled and 13 of them(81.25％) were successfully managed under intranasal midazolam. No severe side effects were observed and the mean Houpt score was 4.00±1.56. ConclusionIntranasal midazolam showed satisfactory sedation effect and safety in this study, while a more definite conclusion will require further studies on larger samples. |
| keywords:Intranasal Sedation Midazolam Pediatric dental treatment fear |
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