| OCT检测人离体牙根部早期脱矿的实验研究 |
| 投稿时间：2010-02-26 修订日期：2010-06-24 点此下载全文 |
| 引用本文：王冠华,李燕妮,姚晖,孟卓,张林朴,梁雨,连小丽,万木森,代晓华,石博雅,刘铁根,姚晓天.OCT检测人离体牙根部早期脱矿的实验研究[J].医学研究杂志,2010,39(9):36-39 |
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| 基金项目:国家自然科学基金面上项目（30770597）;天津市口腔医院重点科技基金资助项目 |
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| 中文摘要:目的利用全光纤OCT系统对人离体牙根部早期人工脱矿模型进行扫描，探讨OCT检出早期根龋的可行性。方法选取正畸拔除的无龋坏、色素沉着、缺损的人离体恒牙3颗，应用脱矿液进行处理，在脱矿时间为0、6、24、72h分别采用OCT进行检测得到二维图像，观察图像特点并计算图像的平均灰度值。将脱矿72h的样本应用偏光显微镜进行检测，将偏光显微镜图像与OCT图像进行比较。结果在OCT二维图像中脱矿6h的样本未见明显的信号增强带，而脱矿24h和72h样本表现为脱矿区信号增强。脱矿区域平均灰度值随脱矿时间的延长而增大，最早发生OCT可见脱矿的时间为脱矿后24h。对于脱矿72h样本，OCT图像的形态学观察结果与偏光显微镜下组织学观察结果相一致。结论OCT能够检出脱矿24h的离体人牙根表面的改变，从而证实OCT具有检出早期牙根表面脱矿的能力。揭示OCT在早期根龋的量化诊断中具有良好的应用前景。 |
| 中文关键词:光学相干断层扫描（OCT） 人牙根部 早期脱矿 平均灰度值 检测 |
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| Study of Detection of Artificial Demineralization on Exposed Surfaces of Tooth Roots with Optical Coherence Tomography |
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| Abstract:ObjectiveTo assess the possibility of detecting artificial demineralization on exposed root surfaces using optical coherence tomography (OCT). MethodsThree human teeth free of caries, pigmentation and deterioration, were extracted and then the samples were exposed to demineralization solution. The samples that exposed to demineralization solution at 0, 6, 24 and 72h were detected by OCT. Then the characteristics and average gray values of OCT images of the testing area were observed and assessed. The sample which had been demineralized for 72h was measured by polarization microscope, and compared with the measurements from OCT. ResultsThere was no detectable demineralization on the samples demineralized for 6h in the OCT images, while the signals of demineralized areas enhanced on the samples demineralized for 24 and 72h. The average gray values of the demineralization areas increased as the demineralization time extended. OCT could detect the demineralization changes of testing areas on root surfaces of the human teeth as early as 24h. The images obtained by OCT were consistent with the ones of the corresponding sites obtained by polarization microscope. ConclusionOCT could detect the demineralization changes of testing areas on root surfaces of the human teeth as early as 24h. OCT could detect early demineralization on root surfaces of human teeth，which suggested the perspective of OCT in quantitative diagnosis of early root caries. |
| keywords:Optical coherence tomography Human dental root Early demineralization Average gray values Detection |
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