| 结直肠癌患者血清瘦素、脂联素和抵抗素水平的临床分析 |
| 投稿时间：2010-04-01 点此下载全文 |
| 引用本文：路璐,李翼,马启玲,韩佩珍.结直肠癌患者血清瘦素、脂联素和抵抗素水平的临床分析[J].医学研究杂志,2010,39(9):78-80 |
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| 中文摘要:目的研究结直肠癌患者血清瘦素、脂联素和抵抗素水平的变化。方法入选30例结直肠癌患者（病例组），另选30例健康体检者为正常对照组。采用酶联免疫吸附分析法检测血清瘦素、脂联素和抵抗素水平。结果病例组的瘦素和脂联素水平均高于正常对照组，病例组的抵抗素水平低于正常对照组。结论血清中抵抗素和脂联素的含量在结直肠癌中发挥着重要的作用，瘦素水平对指导临床实践具有重要的临床价值。 |
| 中文关键词:瘦素 脂联素 抵抗素 结直肠癌 |
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| Study on Serum Leptin，Adiponectin and Resistin Concentration in Patients with Colorectal Cancer |
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| Abstract:ObjectiveTo investigate the concentration of leptin， adiponectin and resistin in patients with colorectal cancer. MethodsThe serum concentration of leptin,adiponectin and resistin was investigated by ELISA in 30 patients with colorectal cancer and in 30 healthy controls. ResultsThe serum concentration of leptin and adiponectin in colorectal cancer patients was lower than that in controls (P<0.05;P<0.05, respectively).The serum concentration of resistin in colorectal cancer patients was higher than that in controls(P<0.05). ConclusionSerum concentration of adiponectin and resistin may play an important role in colon carcinogenesis.Leptin may possibly have the prognostic value in clinical practice. Serum leptin levels are closely related to the diseases process of prognostic value． |
| keywords:Leptin Adiponectin Resistin Colorectal cancer |
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