| 正常女青年畸变产物耳声发射的对侧抑制效应研究 |
| 投稿时间：2010-06-29 点此下载全文 |
| 引用本文：薛飞,李泽卿,王天友,韩援朝,王秋萍.正常女青年畸变产物耳声发射的对侧抑制效应研究[J].医学研究杂志,2010,39(12):130-131 |
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| 中文摘要:目的观察有/无对侧声刺激条件下正常女青年畸变产物耳声发射（distortion product otoacoustic emissions, DPOAE）的变化，探讨DPOAE对侧抑制效应的作用机制及其在疾病诊断中的意义。 方法利用MADSEN公司的CAPELLA全功能耳声发射分析仪对20例（40耳）正常女青年在有/无对侧声刺激两种条件下行DPOAE测试，比较前后两次的DPOAEs听力图（DP-gram）。 结果对侧声刺激作用下DPOAE的DP-gram幅值在750、1000、1500、2000Hz处降低明显，相反在高频6000、8000Hz处的DP-gram幅值升高。 结论正常女青年对侧声刺激条件下DPOAE的DP-gram幅值在低频降低明显，提示脑干内侧橄榄耳蜗系统（medial olivocochlear system, MOCS）对耳蜗低频区外毛细胞有抑制性调控作用，而在高频区外毛细胞的对侧抑制效应消失。 |
| 中文关键词:畸变产物耳声发射 对侧抑制效应 内侧橄榄耳蜗系统 |
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| Contralateral Suppression Effects of Distortion Product Otoacoustic Emissions in Young Women with Normal Hearing |
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| Abstract:ObjectiveTo study the changes of distortion product otoacoustic emissions (DPOAEs) with or without contralateral white noise stimulation in young women with normal hearing, and to discuss the mechanism of contralateral suppression of DPOAEs and its significance in the diagnosis of hearing loss. MethodsThe DPOAEs were examined with or without contralateral white noise stimulation in 20 young women with normal hearing (40 ears) by CAPELLATM Otoacoustic Emissions Test System. The results of DPOAEs-gram of each woman with or without contralateral white noise stimulation were recorded and analyzed. ResultsThe DP-gram amplitude with contralateral white noise stimulation was suppressed obviously in the frequency of 750，1000，1500 and 2000Hz, but the DP-gram amplitude was increased in the frequency of 6000 and 8000Hz. ConclusionThe DP-gram amplitudes with contralateral white noise stimulation were suppressed obviously at low frequencies in young women with normal hearing. It seemed that the outer hair cells of low frequency area were at the state of suppression by the brain stem medial olivocochlear system, but the outer hair cells of high frequency area were not at the state of suppression. |
| keywords:Distortion product otoacoustic emissions Contralateral suppression effect Medial olivocochlear system |
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