孕期打鼾对胎儿宫内生长发育的影响
投稿时间:2010-09-22  修订日期:2011-01-19  点此下载全文
引用本文:李美丽,蔡晓红,倪丽艳,张焕改,俞晨艺,宣妙燕,谢于鹏,吕杰强.孕期打鼾对胎儿宫内生长发育的影响[J].医学研究杂志,2011,40(3):51-55
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作者单位
李美丽 温州医学院附属第二医院、育英儿童医院儿内呼吸科、宁波市妇女儿童医院儿科 
蔡晓红 温州医学院附属第二医院、育英儿童医院儿内呼吸科 
倪丽艳 耳鼻喉科 
张焕改 温州医学院附属第二医院、育英儿童医院儿内呼吸科、河北省邢台市人民医院新生儿科 
俞晨艺 温州医学院附属第二医院、育英儿童医院儿内呼吸科 
宣妙燕 温州医学院附属第二医院、育英儿童医院儿内呼吸科 
谢于鹏 温州医学院附属第二医院、育英儿童医院儿内呼吸科、温州医学院附属第一医院睡眠医学中心 
吕杰强 妇产科 
基金项目:国家计生委科技司基金资助项目(C1-52)
中文摘要:目的探讨孕期打鼾对胎儿宫内生长发育的影响。方法选择2006年1月~2008年2月在笔者医院产科门诊建卡登记并分娩的孕妇601例,在妊娠第13周、28周及分娩前调查孕妇睡眠打鼾情况、测量孕妇生理生化指标、监测各孕期胎儿生长发育,并追踪至产后记录新生儿资料。根据孕妇打鼾情况,分为孕早期打鼾组、孕中期打鼾组、孕晚期打鼾组和非打鼾组。结果与非打鼾组比较,打鼾组孕妇BMI、腹围在孕早、中、晚期均明显增加,差异有统计学意义(P均<0.05)。收缩压在孕早期无变化,孕中、晚期明显增加,差异有统计学意义(P<0.05);舒张压在孕早、中期无变化(P>0.05)。孕晚期明显增加,差异有统计学意义(P<0.05);打鼾组间孕妇不同孕期BMI、腹围、收缩压及舒张压变化两两比较,差异均无统计学意义(均P>0.05)。孕早、中期打鼾组早产发生率均明显高于非打鼾组,差异有统计学意义(P<0.05),孕晚期打鼾组与非打鼾组比较差异无统计学意义(P>0.05)。打鼾组间早产发生率比较差异无统计学意义(P<0.05)。孕早、中期打鼾组剖宫产发生率均明显高于非打鼾组,差异有统计学意义(P<0.05),孕晚期打鼾组和非打鼾组比较,差异无统计学意义(P>0.05),孕早期和孕中期打鼾组比较无统计学差异,但均高于孕晚期打鼾组,差异有统计学意义(P<0.05)。根据RR分析,孕早期、中期打鼾是早产和剖宫产的危险因素。胎儿生长发育及新生儿相关疾病发生率各组比较无统计学差异(P均>0.05)。结论打鼾使孕妇BMI、腹围增加,血压升高,增加胎儿早产、剖宫产的发生率,应加强打鼾孕妇的围生期保健,早期干预、预防胎儿出生缺陷的发生。
中文关键词:打鼾  妊娠  胎儿生长发育
 
The Effects of Snoring During Pregnancy on Fetal Growth and Development
Abstract:ObjectiveTo discuss the effect of snoring during pregnancy on fetal growth and development. MethodsThe study was performed at our hospital from January 2006 to February 2008. A total of 601 pregnant women being in clinic or the ward were enrolled and followed up until the fetus were born. A questionnaire survey about snoring occur was performed. Physiological and biochemical parameters in the 13th,28th week of pregnancy and before delivery were measured. The pregnancy outcome was recorded.The pregnancy fetal growth and development were monitored.And the neonatal data were recorded. According to maternal snoring,these subjects were divided into the first, the second and the third trimester snoring group and non-snoring group. ResultsCompared with non-snoring group, the BMI and abdominal perimeter in snoring group of every trimester increased significantly (P<0.05). There was no significant difference about the systolic blood pressure of snoring group in the first trimester (P>0.05), but it increased significantly in the second and the third trimester (P<0.05). There was no significant difference about the diastolic blood pressure of snoring group in the first and the second trimester(P>0.05), but it increased significantly in the third trimester(P<0.05). There was no significant difference about the BMI, abdominal perimeter and blood pressure among the snoring groups of every trimester (P>0.05). The incidence of premature birth in the first and second trimester snoring groups was higher than that in the non-snoring group. There was no significant difference between the third trimester snoring group and the non-snoring group. There was no significant difference among the snoring groups of every trimester about the incidence of premature birth. The incidence of the abdominal delivery in the first and second trimester snoring group was higher than that in the non-snoring group. But there was no significant differenc between the third trimester snoring group and the non-snoring group. The incidence of the abdominal delivery between the first and second trimester snoring group was not significantly different, but they were both higher than that in the third trimester snoring group(P<0.05). The snore in first and second trimester was the risk factor for premature birth and abdominal delivery. There was no significant difference about the incidence of fetal growth and neonatal-related diseases amony every group (P>0.05). ConclusionThe snore leads to pregnant women′s BMI, abdominal circumference increasing, blood pressure escalating, fetal prematurity and abdominal delivery increasing, so we should pay more attentions to them in their perinatal stage. We should interfere in them early, in order to prevent the occurrence of fetal birth defects.
keywords:Snoring  Pregnancy  Fetal growth and development
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