| 中药治疗痰瘀互结型阻塞性睡眠呼吸暂停综合征的临床观察 |
| 投稿时间：2010-09-28 修订日期：2011-03-07 点此下载全文 |
| 引用本文：王春娥,诸晶,严桂珍.中药治疗痰瘀互结型阻塞性睡眠呼吸暂停综合征的临床观察[J].医学研究杂志,2011,40(3):80-82 |
| DOI：
|
| 摘要点击次数: 1391 |
| 全文下载次数: 1013 |
|
| 基金项目:福建省教育厅科技基金资助项目（JB10080） |
|
| 中文摘要:目的观察中药“鼾症一号方”治疗痰瘀互结型阻塞性睡眠呼吸暂停综合征（obstructive sleep apnea syndrome，OSAS）的临床疗效。方法30例痰瘀互结型OSAS患者入选为治疗组，另随机选取30例OSAS患者为对照组。除一般性治疗外，治疗组给予“鼾症一号方”治疗3个月，对照组不予其他治疗。比较两组治疗前后中医证素积分和西医睡眠监测指标差异。结果两组中医证素积分、呼吸暂停－低通气指数（AHI）、夜间最低血氧饱和度均有改善，治疗组改善更明显，差异有统计学意义。证候积分，治疗前9.53±1.36比治疗后4.70±1.06，P<0.05;AHI，治疗前33.34±9.01次/小时比治疗后12.28±6.45次/小时，P<0.05；夜间最低血氧饱和度，治疗前69.73%±11.44%比治疗后83.08%±5.36%，P<0.05。对照组前后比较差异无统计学意义，证候积分，治疗前9.07±1.21比治疗后8.87±1.29，P>0.05；AHI，治疗前30.52±5.89次/小时比治疗后27.20±5.99次/小时，P>0.05，夜间最低血氧饱和度，治疗前71.43%±6.67%比治疗后73.62%±6.39%，P>0.05。结论“鼾症一号方”治疗阻塞性睡眠呼吸暂停综合征疗效可靠，耐受性好，无不良反应。 |
| 中文关键词:中药治疗 阻塞性睡眠呼吸暂停综合征 痰瘀互结型 |
| |
| ffects of Chinese Medicinal Herbs on Phlegm and Blood Stasis Type of Obstructive Sleep Apnea Syndrome |
|
|
| Abstract:ObjectiveTo evaluate the efficacy of Chinese medical herbs "the 1st snoring prescription" for phlegm and blood stasis type of obstructive sleep apnea syndrome. MethodsThirty cases of phlegm and blood stasis type patients with OSAS were selected for the treatment group and the other 30 cases of OSAS patients were randomly selected as the control group. In addition to general treatment, the cases in treatment group were given "the 1st snoring prescription" for 3 months, while no other treatment to control group. Then integral elements of TCM and Western medicine sleep monitoring indicators were compared between the two groups before and after treatment.ResultsTwo points on integral elements of TCM, apnea - hyperpnoea index (AHI), lowest nocturnal oxygen saturation were improved in some degree, however these indscators in the treatment group improved more significantly and the difference was statistically significant,with integral elements of TCM, 9.53±1.36 vs 4.70±1.06, P<0.05,AHI, 33.34±9.01 vs 12.28±6.45,P<0.05,lowest nocturnal oxygen saturation, 69.73%±11.44% vs 83.08%±5.36%,P<0.05,and there was no adverse event and toxic effect seen in this group.Whereas there was no significant improvement seen in control group after 3 months,with integral elements of TCM, 9.07±1.21 vs 8.87±1.29, P>0.05;AHI, 30.52±5.89 vs 27.20±5.99, P>0.05,lowest nocturnal oxygen saturation, 71.43%±6.67% vs 73.62%±639%,P>0.05.ConclusionChinese medical herbs "the 1st snoring prescription" was effective for phlegm and blood stasis type of obstructive sleep apnea syndrome,and was well tolerated,with for adverse event and toxic effect. |
| keywords:Herb therapy Obstructive sleep apnea syndrome Phlegm and blood stasis type |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
