| 4160例婴幼儿腹泻轮状病毒感染情况分析 |
| 投稿时间：2010-07-13 点此下载全文 |
| 引用本文：李方去,刘彩霞,蒋伟燕.4160例婴幼儿腹泻轮状病毒感染情况分析[J].医学研究杂志,2011,40(3):83-85 |
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| 基金项目:温州市科技局项目（Y20070134） |
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| 中文摘要:目的分析温州市6岁以下婴幼儿腹泻轮状病毒的感染情况。方法利用胶体金法检测标本中A群轮状病毒抗原，用聚丙烯酰胺凝胶电泳进行核酸分型。结果2007～2009年轮状病毒检测的阳性率分别为46.1%、42.7%、30.0%，在6个月~2岁腹泻患儿中检出率最高，最高达40%。每年的2月、5月和10~11月是感染的高峰期。引起婴幼儿腹泻的轮状病毒以长型为主，占94.4%，其中长型以L1型为主。结论轮状病毒是引起春秋季节6个月~2岁婴幼儿腹泻的主要病原体。轮状病毒不同电泳型引起的临床症状差异明显。 |
| 中文关键词:婴幼儿腹泻 轮状病毒 PAGE技术 分型 |
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| Analysis on the Characteristics of Infections Caused by Rotavirus Among 4160 Infants with Diarrhea |
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| Abstract:ObjectiveTo investigate the prevalence of infections caused by rotavirus among infants with diarrhea aged less than 6 years old in Wenzhou, China. MethodsColloidal gold test was used to detect the group A antigen of rotavirus. The genotypes of rotavirus were determined by polyacrylamide gel electrophoresis. ResultsThe positive rates of rotavirus in 2007, 2008 and 2009 were 46.1%, 42.7% and 30.0%, respectively. The prevalence of rotavirus among infants with diarrhea aged from 6 months to 2 years was high to 40%. The peak of infection caused by rotavirus occurred in February, May, October and November of every year. Long type of rotavirus isolates causing infantile diarrhea accounted for 94.4%, in which the type L1 was the most prevalent type. ConclusionRotavirus is the major pathogen causing infantile diarrhea of the patients aged from 6 months to 2 years in spring and autumn. Different electrophoresis types of rotavirus can cause different clinical symptoms. |
| keywords:Infantile diarrhea Rotavirus PAGE Type |
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