| 直肠癌淋巴结转移风险因素分析 |
| 投稿时间：2010-06-12 点此下载全文 |
| 引用本文：蒋军,周济春,张喜平,张勤,余建法,裘华森.直肠癌淋巴结转移风险因素分析[J].医学研究杂志,2011,40(3):125-128 |
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| 中文摘要:目的探讨直肠癌淋巴结转移及其风险因素。方法回顾性分析108例行全直肠系膜切除术患者临床资料，分析淋巴结转移和风险因素的关系。结果全组病例淋巴结转移率38.9%，检出淋巴结8.97±5.067枚，淋巴结阳性率18.8%，分析显示直肠癌的淋巴结阳性率与患者的年龄、性别、肿瘤大小、术式、瘤体位置、GST-π表达均无明显相关(P>0.05)，而与肿瘤的大体类型、浸润深度、分化程度、检出淋巴结数目显著相关(P<0.05)，其中肿瘤浸润肠壁深度是影响淋巴结转移的最重要风险因素。结论直肠癌淋巴结转移与肿瘤的浸润深度、分化程度、大体类型、检出淋巴结数目显著相关。 |
| 中文关键词:直肠癌 淋巴结转移 风险因素 |
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| Analysis of Risk Factors for Lymph Node Metastasis in Rectal Cancer |
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| Abstract:ObjectiveTo investigate the characteristics of lymph node metastasis in rectal cancer. MethodsA total of 108 cases of rectal carcinoma who underwent TME resection were retrospectively studied. The association between lymph node metastasis and clinic-pathologic risk factors were evaluated. ResultsThe whole rate of lymph node metastasis of rectal cancer in this study was 38.9%. The number of examined lymph nodes was 8.97±5.067. The whole positive rate of lymph node metastasis was 18.8%. Age, gender, tumor location, size, modus operandi and GST-πexpression were not significantly correlated with lymph node metastasis (P>0.05). Depth of invasion, histological differentiation, macroscopic type and examined lymph nodes were statistically significant as risk factors for lymph node metastasis (P<0.05). The depth of invasion was the most important risk factor of lymph node metastasis. ConclusionDepth of tumor invasion, grade of histological differentiation, macroscopic type and the number of examined lymph nodes are significantly correlated with lymph node metastasis. |
| keywords:Rectal cancer Lymph node metastasis Risk factor |
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