| 通心络胶囊联合文拉法辛对脑梗死后抑郁的临床研究 |
| 投稿时间：2010-11-30 点此下载全文 |
| 引用本文：黄欢捷,邵蓓,殷为勇,牛晓婷.通心络胶囊联合文拉法辛对脑梗死后抑郁的临床研究[J].医学研究杂志,2011,40(5):92-93 |
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| 中文摘要:目的探讨通心络胶囊联合文拉法辛治疗脑梗死后抑郁的临床疗效。方法60例脑梗死后抑郁患者随机分为对照组（30例）和治疗组（30例），在常规治疗的基础上，对照组给予盐酸文拉法辛缓释胶囊治疗，治疗组予盐酸文拉法辛缓释胶囊和通心络胶囊治疗，两组疗程均为4周。比较两组疗效和治疗前后汉密尔顿抑郁量表、Barthel 指数评分、血清hs-CRP水平。结果治疗组疗效优于对照组(P<0.05);治疗后两组间HAMD、Barthel评分、血清hs-CRP水平有显著性差异(P<0.05)。结论通心络胶囊联合文拉法辛治疗脑梗死后抑郁患者，能更有效改善患者的抑郁症状,提高患者日常生活能力。 |
| 中文关键词:通心络胶囊 文拉法新 脑梗死 抑郁 |
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| Effect of Tongxinluo Capsule Combined Venlafaxine on the Depression after Cerebral Infarction |
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| Abstract:ObjectiveTo investigate the effect of Tongxinluo capsule combined venlafaxine in the treatment of depression after cerebral infarction. MethodsSixty patients with depression after cerebral infarction were randomly divided into comparison group (30)and treatment group (30). On the basis of basic treatment, patients in control group were given venlafaxine, observation group were given venlafaxine and Tongxinluo capsule，with the course of 4 weeks.Efficacy of 2 groups, and the Hamilton Depression Scale,and modified Barthel index,and level of hs-CRP before and after treatment were compared. ResultsEfficacy of treatment group was better than that of the control group (P<0.05). There was significant difference between the two groups in HAMD,MBI,level of hs-CRP 4 weeks after treatment (P<0.05).ConclusionTongxinluo capsule combined venlafaxine in the treatment of depression after cerebral infarction patients can be more effective in improving patients with depressive symptoms, and improving the patients activities of daily living. |
| keywords:Tongxinluo capsule Venlafaxine Cerebral infarction Depression |
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