| 老年肺炎与胃食管反流的关系探讨 |
| 投稿时间：2010-08-15 点此下载全文 |
| 引用本文：吴旻,厉朝喜,管小娟,戴一扬.老年肺炎与胃食管反流的关系探讨[J].医学研究杂志,2011,40(5):111-114 |
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| 中文摘要:目的探讨老年人肺炎与胃食管反流（GER）的关系。方法采用便携式24h pH动态监测仪记录食管下端pH值变化。观察组 68例年龄>60岁的老年肺炎患者，其中年龄>80岁32例,平均年龄78.3±15.9岁, 对照组选择无肺炎的老年患者30例，平均年龄76.2±11.8岁。 结果观察组各项反流指标检测结果中的 6项反流指标均高于对照组（P＜0.01)，观察组中GER检出率79.4％（54/68），显著高于对照组（P＜0.01) ，但有症状仅占8例，发生率为14.8％（8/54）。肺炎合并GER中年龄＞80岁的高龄老年患者在pH＜4总时间百分比、卧位pH＜4总时间百分比、＞5min反流次数均高于年龄60～80岁老年患者，差异有显著性（P＜0.01）。结论胃食管反流是老年肺炎的重要发病机制，多无典型症状，＞80岁的的老年患者肺炎的发生与胃食道反流关系更密切。 |
| 中文关键词:老年 肺炎 食管pH检测 胃食管反流 |
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| The Relationship between Pneumonia and Gastroesophageal Reflux in the Senile |
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| Abstract:ObjectiveTo investigate the relationship between pneumonia and gastroesophageal reflux (GER) in the senile. MethodsUsing a portable 24-hour esophageal pH monitoring instrument,we recorded pH in lower esophagus. Sixty-eight pneumonia patients in observing group with an age＞60 years were enrolled, including 32 cases with an age＞80 years and a mean age of 78.3 ± 159.Thirty non-pneumonia patients in control group with a mean age 76.2±11.8 years were enrolled. ResultsThe reflux indexes in observing group were higher than those in control group (P<0.01). The GER rate of 79.4% (54/68) was significantly higher than that in the control group (P<0.01), but only 8 cases had symptom, and the rate was 14.8% (8/54).For pneumonia complicated with GER,patients over 80 years old were significantly higher than those aged 60~80 years old patients in the total time of pH <4 percentage,supine pH <4 total time percentage and ＞5min reflux episodes, (P<0.01). ConclusionGastroesophageal reflux has an important role in the pathogenesis of senile pneumonia.Most patients have no typical symptoms. The incidence of pneumonia and GER have dosely correlation in senile patients with an age＞80 years. |
| keywords:Senile Pneumonia Esophageal pH monitoring Gastroesophageal reflux |
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