| 降糖通脉胶囊治疗血瘀型糖尿病周围神经病变的疗效观察 |
| 投稿时间：2010-12-06 修订日期：2010-12-29 点此下载全文 |
| 引用本文：周孝德,周静,周荣,常亚霖,赵国福,刘作东,鲁彦.降糖通脉胶囊治疗血瘀型糖尿病周围神经病变的疗效观察[J].医学研究杂志,2011,40(8):129-132 |
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| 中文摘要:目的观察降糖通脉胶囊治疗血瘀型糖尿病周围神经病变的疗效。 方法选择2005年6月~2008年6月笔者医院住院糖尿病周围神经病变患者80例。随机分为两组,对照组40例，给予DPN 基础治疗；治疗组40例，在对照组治疗基础上加用降糖通脉胶囊连续治疗3个月。观察两组治疗前后患者症状、体征，测量空腹血糖（FPG）、血液流变学指标及正中神经和腓总神经的运动神经传导速度(MNCV)和感觉神经传导速度(SNCV)。 结果治疗组临床疗效总有效率（82.5%）高于对照组，空腹血糖(治疗前9.8±2.3mmol/L比治疗后7.4±1.6mmol/L，P<0.05)下降，血液流变学指标均降低（P<0.05）,MNCV和 SNCV加快（P<0.05)。且治疗组各项检测指标均优于对照组(P<0.05)。结论降糖通脉胶囊降低血糖、血脂，改善血液流变学指标，加快神经传导速度，对治疗血瘀型糖尿病周围神经病变有较好的治疗效果。 |
| 中文关键词:降糖通脉胶囊 糖尿病周围神经病变 疗效 |
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| Clinical Study of Blood Stasis Typing Diabetic Peripheral Neuropathy Treated by Jiangtangtongmai Capsule |
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| Abstract:ObjectiveTo observe the therapeutic effect of Jiangtangtongmai capsule in treating diabetic peripheral neuropathy of blood stasis type. MethodsEighty hospitalized patients with diabetic peripheral neuropathy,selected from June 2005 to June 2008,were divided into two groups in random.Control group of 40 cases were given DPN foundation treatment.And treatment group,based on control group therapy,were added to Jiangtangtongmai capsule for three months.Symptoms and signs of patients before and after treatment were observed.Fasting plasma glucose (FPG),hemorheology and nerve conductive velocity (NCV) of Median Nerve and Peroneal Nerve were measured. ResultsThe total effective rate of the clinical effect in treatment group was higher than that in control group. FPG in treatment group was significantly decreased after treatment,and the change had difference with that in control group (treatment group: -2.4±0.5 vs.control group: -1.3±0.1,P<0.05).Blood parameters in treatment group,including blood viscosity,lipids and so on,was dropped after treatment (P<0.05).Motor nerve conduction velocity (MNCV) and sensory nerve conduction velocity (SNCV) in treatment group were obviously accelerated through treatment,and the changes had difference with those in control group (P<0.05). ConclusionJiangtangtongmai capsule can drop blood glucose and blood lipids,improve hemorheology,and speed up NCV,and has the effect in treating diabetic peripheral neuropathy of blood stasis type. |
| keywords:Jiangtangtongmai capsule Diabetic peripheral neuropathy Therapeutic effect |
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