| 黄芪注射液治疗扩张型心肌病疗效的系统评价 |
| 投稿时间：2011-03-07 修订日期：2011-03-28 点此下载全文 |
| 引用本文：卞洲艳,唐其柱,李芳芳,魏文.黄芪注射液治疗扩张型心肌病疗效的系统评价[J].医学研究杂志,2011,40(11):70-72 |
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| 基金项目:高等学校博士学科点专项科研基金资助项目（新教师类）（20100141120070） |
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| 中文摘要:目的评价中药黄芪注射液治疗扩张型心肌病的疗效。方法计算机检索PubMed（1966~2011年1月）、Cochrane图书馆2011年第1期、中国期刊全文数据库（1979~2010年）、中国医学生物文献光盘数据库。按纳入、排除标准纳入合格的随机对照研究并对其方法学质量进行评价后，采用RevMan 5.0.25 软件进行Meta分析。结果共纳入5篇研究，总计353例患者。Meta分析结果表明黄芪注射液+西医基础治疗在改善扩张型心肌病患者的症状、体征、心电图与心功能异常以及实验室各项指标等方面，优于单纯的西医基础治疗，其OR（95% CI）为4.50（2.33~8.70）。 结论黄芪注射液作为西医基础治疗的辅助药物，在改善扩张型心肌病患者的症状、体征、心电图与心功能异常以及实验室各项指标等方面优于单纯的西医基础治疗。 |
| 中文关键词:黄芪注射液 扩张型心肌病 疗效 系统评价 |
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| Systematic Reviews of the Therapeutic Effect of Huangqi on Dilated Cardiomyopathy |
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| Abstract:ObjectiveTo review the therapeutic effect of the traditional Chinese medicine-radix astragali for dilated cardiomyopathy. MethodThe randomized controlled trails which accord with the inclusive/exclusion criteria were gathered from PubMed (1966 to 2011), Cochrane library (2011, No.1), CSJD (1979 to 2010) and CBMdisc through searching on the computer, and the methodology quality of every research was evaluated and then analyzed with RevMan 5.0.25 software. ResultsFive randomized controlled trials were included, totally 353 cases of patients. As the Meta-analysis showed, the therapeutic effect of radix Astragali combined with western medicine basic therapy was better than that of simple western medicine basic therapy in aspects of improving the symptom, physical sign, electrocardiogram, cardiac disfunction and biochemical indicator of the dilated cardiomyopathy patients (OR=4.50, 95%CI 2.33-870). ConclusionRadix astragali, as the ancillary drug of western medicine basic therapy, take better therapeutic effect than that of simple western medicine basic therapy of dilated cardiomyopathy. |
| keywords:Radix astragali/ huangqi Dilated cardiomyopathy Therapeutic effect Systematic reviews |
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