甲状腺腺叶切除术后甲状腺功能变化的临床观察
投稿时间:2011-01-30  修订日期:2011-02-24  点此下载全文
引用本文:王会元,李非,罗斌.甲状腺腺叶切除术后甲状腺功能变化的临床观察[J].医学研究杂志,2012,41(1):136-138
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作者单位
王会元 首都医科大学宣武医院普通外科 
李非 首都医科大学宣武医院普通外科 
罗斌 首都医科大学宣武医院普通外科 
中文摘要:目的探讨甲状腺腺叶切除术后甲状腺功能低下(甲低)的发生率及其相关因素。方法回顾性分析2009年因良性疾患由同一组医生行甲状腺腺叶切除术68例患者的临床资料,和术前、术后1个月与术后3个月的甲状腺功能结果,判断甲状腺腺叶切除术后甲低的发生率及其危险因素。结果术后第1个月时甲低发生率为20.6% (14/68);在第3个月时为13.0% (9/68)。甲低组(n=9)的平均年龄高于甲状腺功能正常组(n=59)(分别为57.2±12.6岁 vs 48.8±11.5岁, P=0.046),而且甲低组的术前TSH水平的平均值也较高(分别为2.17±0.90μU/L vs 1.45±0.68μU/L, P=0.007)。而患者的性别、病理类型以及切除腺叶侧别与术后是否发生甲低无关。结论甲状腺叶切除术后甲低的发生率为13.0%,年长患者以及术前TSH水平较高者应当密切监测甲状腺功能。
中文关键词:甲状腺叶切除术  甲状腺功能  甲状腺结节
 
Thyroid Function Alterations after Hemi-thyroidectomy
Abstract:ObjectiveTo investigate the incidence of hypothyroidism after hemi-thyroidectomy and the associated relevant risk factors.MethodsWe conducted a retrospective review of all patients undergoing hemithyroidectomy for benign diseases in 2009 by the same surgeons. Thyroid function was tested preoperatively, 1 month and 3 months postoperatively. Risk factors of hypothyroidism were also analysed. ResultsHypothyroidism was diagnosed in 20.6% patients(14/68) and 13.0% patients(9/68) by the end of 1 month and 3 months postoperatively, respectively. Increased ages (57.2±12.6 years vs 48.8±11.5 years,P=0.046) and higher preoperative thyrotropin levels (2.17±0.90μU/L vs 1.45±0.68μU/L,P=0.007) were more common in hypothyroidism group. There was no correlation between sex, pathology or the side of lobectomy with hypothyrodisim. ConclusionThe incidence of hypothyroidism after hemithyroidectomy was 13.0%. The patients with an increased age or a relatively high preoperative TSH level need to be monitored closely.
keywords:Hemi-thyroidectomy  Thyroid function  Thyroid nodule
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