多中心性乳腺导管内癌的诊治分析
投稿时间:2011-07-04  修订日期:2011-08-22  点此下载全文
引用本文:史东波,周官保,柯孔亮.多中心性乳腺导管内癌的诊治分析[J].医学研究杂志,2012,41(4):148-150
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作者单位
史东波 宁波第一医院肿瘤科 
周官保 宁波第一医院肿瘤科 
柯孔亮 宁波第一医院肿瘤科 
中文摘要:目的探讨多中心性乳腺导管内癌的临床特点,以提高早期诊断率。方法回顾分析笔者医院2000年1月~2010年 12月诊治的24例多中心性乳腺导管内癌患者的临床资料。结果本组24例患者中5例伴有乳头溢液,19例术前体检无阳性发现。在术前X线钼靶摄影检查的阳性率为87.5%,主要特点是存在弥漫性、多发性钙化灶;MRI的阳性率为33.3%,B超无阳性发现。经术中冷冻切片检查证实多中心性乳腺导管内癌后,均行全乳房切除和同侧腋窝组淋巴结清扫术。结论X线钼靶摄影检查早期多中心性乳腺导管内癌主要特点是存在多发性、散在的细小钙化,该疾病虽然病变范围广泛但仍属早期肿瘤,经手术、放化疗等综合治疗后预后良好。
中文关键词:导管内癌  X线钼靶摄影检查  MRI
 
Diagnosis and Treatment on Ductal Carcinoma in Situ
Abstract:ObjectiveTo discuss the clinical characteristics of multicenter ductal carcinoma in situ to improve the rate of early diagnosis. MethodsA total of 24 cases of multicenter ductal carcinoma in situ were analyzed retrospectivelyfrom January 2000 to December 2010 in our hospital.ResultsAmong the 24 patients, 5 cases were presented with nipple discharge, 19 cases were found with negetive findings. In the preoperative X-ray mammography examination,the positive rate was 87.5%, mainly characterized by a diffuse, multiple calcification.MRI positive rate was 33.3%, and B vltra had no positive results.After confirmed multicentric ductal carcinoma in situ by the intraoperative frozen section examination,all had total mastectomy and ipsilateral axillary lymph node dissection. ConclusionX-ray mammography examination of early multi-center breast ductal carcinoma in situ mainly characterized by a diffuse, multiple small calcified lesions, lesions of the disease.Although the range was broad,it was still early-stage tumor.After surgery, radiotherapy and chemotherapy,the prognosis is good after combined treatment.
keywords:Ductal carcinoma in situ  X-ray mammography examination  MRI
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