前臂静脉和足背静脉芬太尼静脉注射后呛咳反应的比较
投稿时间:2011-08-23  修订日期:2011-09-26  点此下载全文
引用本文:汪小海,王幸双.前臂静脉和足背静脉芬太尼静脉注射后呛咳反应的比较[J].医学研究杂志,2012,41(5):124-126
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作者单位
汪小海 南京大学医学院附属鼓楼医院麻醉科 
王幸双 南京大学医学院附属鼓楼医院麻醉科 
中文摘要:目的比较麻醉诱导时前臂静脉和足背静脉芬太尼静注后呛咳反应的发生率及强度。方法ASAⅠ的择期手术患者40例,随机均分为两组:前臂静脉组(Ⅰ组)、足背静脉组(Ⅱ组),两组静脉注射芬太尼的剂量均为3μg/kg,用药速度均为2s内推入,Ⅰ组于前臂静脉给予芬太尼,Ⅱ组于足背静脉给予芬太尼,记录麻醉前(T0)、芬太尼注射前(T1)及后0.5min(T2)、1min(即插管前,T3)、插管后1min(T4)和2min(T5)时的心率、收缩压及呛咳情况。结果Ⅰ组芬太尼推注后患者呛咳的发生率及强度显著大于Ⅱ组。结论麻醉诱导期间芬太尼(3μg/kg,2s内)足背静脉注射较前臂静脉注射能减少芬太尼给药后其呛咳反应的发生率及强度。
中文关键词:芬太尼  呛咳反应  前臂静脉  足背静脉
 
Compare the Incidence and Severity of Fentanyl-induced Cough Between the Forearm Vein and Dorsal Vein of Foot
Abstract:ObjectiveTo compare the incidence and severity of FIC caused by injecting fentanyl through a vein in the forearm with through dorsal vein of foot.MethodsForty patients of ASA I, aged 18-55 year and weighing 47-78kg, undergoing elective surgical procedures were randomly allocated into two groups consisting of 20 patients. Both groups received i.v. fentanyl (3.0mg/kg) within 2 seconds. Group Ⅰreceived fentanyl through a vein in the forearm, whereas group Ⅱreceived fentanyl through dorsal vein of foot. The incidence of cough was recorded for 1min before the induction of anaesthesia, and graded as none (0 cough), mild(1-2 cough), moderate(3-4 cough) and severe(≥5 cough). ResultsThe incidence of cough was 55% in group Ⅰand 5% in groupⅡ(P<0.05).The severity of cough in group Ⅰwas more than the severity in group Ⅱ. ConclusionComparing with injecting fentanyl through vein of forearm, injecting fentanyl (3.0mg/kg) through dorsal vein of foot significantly reduces the incidence and severity of FIC in majority of the patients.
keywords:Fentanyl  Fentanyl-induced cough  Forearm vein  Ddorsal vein of foot
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