常规超声联合超声造影在鉴别诊断慢性淋巴细胞性甲状腺炎合并甲状腺实性结节中的价值
投稿时间:2014-08-25  修订日期:2014-09-17  点此下载全文
引用本文:杨娟,吴昌财,颜树宏,郑笑娟.常规超声联合超声造影在鉴别诊断慢性淋巴细胞性甲状腺炎合并甲状腺实性结节中的价值[J].医学研究杂志,2015,44(3):97-100
DOI: 10.3969/j.issn.1673-548X.2015.03.027
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作者单位E-mail
杨娟 316021 温州医科大学附属舟山医院超声诊断中心  
吴昌财 316021 温州医科大学附属舟山医院超声诊断中心  
颜树宏 316021 温州医科大学附属舟山医院超声诊断中心  
郑笑娟 316021 温州医科大学附属舟山医院超声诊断中心 zhengxiaojuan7173@126.com 
基金项目:浙江省科技厅公益性技术应用研究计划基金资助项目(2012C23059);舟山市卫生局基金资助项目(2009A02);舟山市科技局基金资助项目(2009043)
中文摘要:目的 通过研究常规超声联合超声造影在鉴别诊断慢性淋巴细胞性甲状腺炎合并甲状腺实性结节的价值, 提高术前诊断的准确率。方法 以2013年1月~2014年8月在舟山医院经手术病理证实的80例慢性淋巴细胞性甲状腺炎患者108个甲状腺实性结节为研究对象, 分析比较其术前常规超声图像表现及超声造影表现, 并以病理结果为金标准绘制ROC曲线, 评价常规超声联合超声造影在慢性淋巴细胞性甲状腺炎合并甲状腺实性结节鉴别诊断中的价值。结果 边界、纵横比、回声、钙化、血流分布、不均匀增强及增强强度7个超声影像特征对诊断恶性结节有较大的参考价值, 联合7项超声影像特征诊断的敏感度为87.1%, 特异性为84.8%, 准确度为86.1%。结论 常规超声联合超声造影对评估慢性淋巴细胞性甲状腺炎合并甲状腺实性结节良恶性有一定的价值, 能明显提高诊断的准确率。
中文关键词:慢性淋巴细胞性甲状腺炎  常规超声  超声造影
 
Diagnostic Value of Contrast-enhanced Ultrasonography Combined with Conventional Ultrasound in Benign and Malignant Solitary Thyroid Nodules with Chronic Lymphocytic Thyroiditis
Abstract:Objective To improve the accuracy of preoperative diagnosis of conventional ultrasound combined with contrast-enhanced ultrasound (CEUS) in the differential diagnosis of thyroid solid nodules with chronic lymphocytic thyroiditis (CLT). Methods Totally 108 thyroid solid nodules with CLT were examed by conventional ultrasound and contrast-enhanced ultrasound, which were confirmed by surgical pathology in Zhoushan Hospital, and there preoperative ultrasound images were revewed. A receiver operator characteris (ROC) curve was constructed to assess the performance. Results Seven ultrasonographic features including margin, aspect ratio, echo, calcification, blood ditribution, heterogeneous enhancement and peak intensity were valuable in the diagnosis of malignant thyroid solid nodule with CLT. When combination of the seven parameters were used for the diognosis of malignant thyroid solid nodules with CLT, the percentage of correct prediction, the sensitivity and specificity were 86.1%, 87.1%, 84.8%, respectively. Conclusion Conventional ultrasoud combined with contrast-enhanced ultrasound were valuable in the differential diagnosis of benign and malignant thyroid solid nodule, and improved the accuracy of preoperative diagnosis.
keywords:Chronic lymphocytic thyroiditis  Conventional ultrasound  Contrast-enhanced ultrasound
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