| 放疗联合射频消融术治疗晚期非小细胞肺癌的临床研究 |
| 投稿时间：2014-07-26 修订日期：2014-09-23 点此下载全文 |
| 引用本文：金靖寅,颜桂明,王仁江,冯晓栋.放疗联合射频消融术治疗晚期非小细胞肺癌的临床研究[J].医学研究杂志,2015,44(4):126-129 |
| DOI：
10.11969/j.issn.1673-548X.2015.04.035 |
| 摘要点击次数: 1325 |
| 全文下载次数: 1396 |
|
|
| 中文摘要:目的 探讨放疗联合射频消融(RFA)治疗非小细胞肺癌的效果。 方法 选择70例非小细胞肺癌患者为研究对象。将70例患者按照数字表法随机分为两组,观察组38例患者,接受常规放疗联合RFA;对照组32例患者,接受常规放疗。对比两组疗效、生存率、复发率、转移率及并发症。 结果 观察组KPS评分明显高于对照组,差异有统计学意义(t=6.238,P=0.000)。观察组治疗有效率明显高于对照组,差异有统计学意义(86.84% vs 62.50%,P<0.01)。两组转移率比较差异无统计学意义(P>0.05);观察组复发率低于对照组,差异有统计学意义(7.89% vs 25.0%,χ2=5.005,P=0.025)。两组1年生存率比较,差异有统计学意义(P<0.05)。两组2年、3年生存率比较,差异无统计学意义(P>0.05)。两组均未发生严重不良反应。 结论 放疗联合RFA治疗晚期非小细胞肺癌,疗效确切,可有效控制肿瘤复发,提高患者近期生存率,且创伤小,安全性高。 |
| 中文关键词:非小细胞肺癌 射频消融术 放疗 疗效 |
| |
| Clinical Research on Radiofrequency Ablation and Adjuvant Radiotherapy Treating Advanced Non-small Cell Lung Cancer |
|
|
| Abstract:Objective To study the effect of radiofrequency ablation and adjuvant radiotherapy treating non-small cell lung cancer. Methods Seventy cases of non-small cell lung cancer patients were selected as the research object. The 70 patients were randomly divided into two groups according to random number table method. In observation groups,38 patients were treated by RFA in combination with conventional radiotherapy.In control group,32 patients were treated by conventional radiotherapy. Curative effect, survival rate, transferring rate, recurrence rate and complications of the two groups were compared. Results KPS score of observation group was obviously higher than that of control group, and the difference was statistically significant (t=6.238, P=6.238).Efficient rate of observation group was obviously higher than that of control group, and the difference was statistically significant (86.84% vs 62.50%, P<0.01). Transferring rate between the two groups had no statistical significance (P>0.05); Recurrence rate of observation group was lower than the control group, and the difference was statistically significant (7.89% vs 25.0%, χ2=5.005, P=0.025).One year survival rate was compared between the two groups, and the difference was statistically significant (P<0.05). Two years, 3 years survival rate were compared between two groups, and there was no statistically significant difference (P>0.05). In the two groups there were no serious adverse reactions. Conclusion RFA combined with radiotherapy treating advanced non-small cell lung cancer has good curative effect, and can effectively control the tumor recurrence, improve the survival rate. And it is minimally invasive, with high safety. |
| keywords:Non-small cell lung cancer Radiofrequency ablation Radiation therapy Curative effect |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
