胃癌术后接受化疗后再次复发因素研究
投稿时间:2014-09-23  修订日期:2014-10-21  点此下载全文
引用本文:刘彩霞,曹冉华,邢智伟,呼群,苏乌云.胃癌术后接受化疗后再次复发因素研究[J].医学研究杂志,2015,44(4):133-135
DOI: 10.11969/j.issn.1673-548X.2015.04.037
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作者单位E-mail
刘彩霞 010059 呼和浩特, 内蒙古医科大学附属医院肿瘤内科  
曹冉华 010059 呼和浩特, 内蒙古医科大学附属医院肿瘤内科  
邢智伟 010059 呼和浩特, 内蒙古医科大学附属医院肿瘤内科  
呼群 010059 呼和浩特, 内蒙古医科大学附属医院肿瘤内科  
苏乌云 010059 呼和浩特, 内蒙古医科大学附属医院肿瘤内科 suwuyun@csco.org.cn 
中文摘要:目的 研究分析胃癌术后接受化疗后再次复发的影响因素。 方法 回顾性分析2009年3月~2011年4月,在笔者医院接受胃癌术后化疗后再复发的65例胃癌患者的临床、病理和生存资料,并采用Logistic多因素回归分析,对影响胃癌在接受化疗后复发的因素进行分析。 结果 在病理资料与复发时间的分析中,患者的性别(t=0.056,P=0.076)与年龄(t=0.320,P=0.063),不会直接影响患者的复发时间;而患者胃癌的分化程度(t=2.23,P=0.002)、切缘(t=5.36,P=0.032)、TMN分期(F=3.68,P=0.018),差异均有统计学意义;Logistic多因素回归分析显示患者的肿瘤直径(OR=3.56,P=0.001)、TNM分期(OR=6.48,P=0.006)以及Borrmann分型(OR=2.52,P=0.003)是胃癌化疗后再次复发的独立危险因素。 结论 胃癌在术后接受化疗后再次复发时间与患者性别、年龄无关,肿瘤直径、TNM分期、Borrmann分型是其再次复发的独立危险因素。
中文关键词:胃癌  再次复发  因素
 
Study on the Factors of Rrecurrence of Gastric Cancer after Chemotherapy Again
Abstract:Objective To research the factors of gastric cancer recurrence in receiving chemotherapy. Methods A retrospective analysis from 2009 March to 2013 April in our hospital were taken, 65 cases with gastric cancer were received chemotherapy treatment and survival data were analyzed, and the multi factor Logistic regression analysis were used, the influencing factors of the relapse after chemotherapy in gastric cancer were analyzed. Results In the analysis of pathological data and time of recurrence: There were not significant difference the patient's sex (t=0.056, P=0.076), age (t=0.320, P=0.063)with recurrent time, there were not directly affect patients with recurrent time; and there were the difference among the patient's degree of differentiation (t=2.230, P=0.002), the cutting edge (t=5.360, P=0.032), TMN staging (F=3.680, P=0.018); multivariate Logistic regression analysis showed that the size of the tumor patients (OR=3.560, P=0.001), TNM staging (OR=6.480, P=0.006) and Borrmann type (OR=2.520, P=0.003) were independent risk factors of relapse of gastric cancer after chemotherapy. Conclusion For gastric cancer patients during chemotherapy again, there are not difference among recurrence time, gender and age. Tumor size, TNM stage and Borrmann type are the independent risk factors of recurrence.
keywords:Metastatic gastric cancer  Relapse  Factor
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