| 不同时间段颅骨修补对脑血流动力学变化的影响 |
| 投稿时间：2014-12-20 修订日期：2015-01-20 点此下载全文 |
| 引用本文：付俊飞,卞戈,李敏,陈岗,杜安东,马东明,李永财.不同时间段颅骨修补对脑血流动力学变化的影响[J].医学研究杂志,2015,44(5):104-107 |
| DOI：
10.11969/j.issn.1673-548X.2015.05.028 |
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| 中文摘要:目的 观察不同手术时间段颅骨缺损修补术对脑血流动力学变化的影响。方法 回顾性分析30例行单侧颅骨缺损修补术患者,根据手术时间分为早期组(<3月)和晚期组(≥3月)。于颅骨修补术前 3~4天和术后 10~14 天,应用 256 排螺旋CT行脑灌注扫描,记录患侧大脑皮质、基底核和丘脑区域灌注图像上 rCBV、rCBF、MTT 及 TTP 等参数值。分析不同颅骨修补时间段的脑血流灌注数据改变量的变化情况。结果 早期颅骨修补组手术前后患侧皮质、基底核区rCBF的改变量[14.94±3.42ml/(100g·min)、14.41±3.98ml/(100g·min)]明显大于晚期组手术前后皮质、基底核区的改变量[10.74±4.04ml/(100g·min)、9.94±5.12ml/(100g·min)],差异有统计学意义(P<0.05),同时早期修补组基底核区的MTT的改变量(-2.10±1.59s)和晚期组(-0.96±1.09s)相比差异有统计学意义(P<0.05)。结论 早期颅骨修补更有利于改善脑灌注。 |
| 中文关键词:颅骨修补 手术时间 脑血流动力学 CT灌注 |
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| Influence of Cranioplasty in Different Surgical Time on Cerebral Hemodynamics |
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| Abstract:Objective To observe the influence of different operation time about cranioplasty on cerebral hemodynamics. Methods Thirty patients who were undergoing early(<3 months) or late(≥3 months) cranioplasty after decompressive craniectomy were analysed retrospectively. We collected data about regional rebral blood volume (rCBV),regional cerebral blood flow (rCBF),mean transit time (MTT) and transit time peak (TTP) at the affected cortex,basal nuclei and thalamus which were recorded by 256 CT perfusion technique,then calculated the changes of these data between 3-4 days before and 10-14 days after surgery and analyzed by the software SPSS 11.5. Results The changes of CBF at injured side cortex [14.94±3.42ml/(100g·min)], basal nuclei[14.94±3.42ml/(100g·min)] in the early group compared with late craniplasty [cortex10.74±4.04ml/(100g·min),basal nuclei 9.94±5.12ml/(100g·min)] were increased statistically (P<0.05).The changes of MTT in the early group (-2.10±1.59s) and late craniplasty (-0.96±1.09s) were also statistically significanct (P<0.05). Conclusion Early craniplasty has potential benefits for cerebral perfusion. |
| keywords:Cranioplasty Operate time Cerebral hemodynamics CT perfusion |
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