中医针刺治疗对慢性支气管炎患者血清炎性介质及临床疗效的影响
投稿时间:2014-10-11  修订日期:2014-11-19  点此下载全文
引用本文:杨瑞春,黎芬芬.中医针刺治疗对慢性支气管炎患者血清炎性介质及临床疗效的影响[J].医学研究杂志,2015,44(6):73-75
DOI: 10.11969/j.issn.1673-548X.2015.06.021
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作者单位E-mail
杨瑞春 530023 南宁, 广西中医药大学第一附属医院 wx1358@163.com 
黎芬芬 530023 南宁, 广西中医药大学附属瑞康医院  
基金项目:广西科技厅科技攻关项目(桂科攻1298003-6-2)
中文摘要:目的 探讨中医针刺治疗对慢性支气管炎患者血清白介素-2(IL-2)、白介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)水平及临床疗效的影响。方法 将60例慢性支气管炎患者按数字表法随机分为中医针刺组(观察组)和对照组,每组30例。对照组给予抗炎、止咳化痰、解痉平喘等治疗;观察组在对照组基础上给予中医针刺治疗。治疗30天后,对比两组患者临床有效率和血清炎性介质IL-2、IL-8及TNF-α水平。结果 观察组总有效率(94.6%)显著高于对照组总有效率74.6%(P<0.05);观察组患者血清IL-2水平显著高于对照组(P<0.05),而IL-8、TNF-α水平显著低于对照组(P<0.05),差异有统计学意义。结论 中医针刺治疗能有效减轻慢性支气管炎患者临床症状及炎性反应,改善机体免疫调节功能。
中文关键词:慢性支气管炎  针刺  炎性介质  疗效
 
Influence of Traditional Chinese Medicine Acupuncture On Serum Inflammatory Mediators And Clinical efficacy In Patients With Chronic Bronchitis
Abstract:Objective To explore the traditional Chinese medicine acupuncture therapy on level of serum in interleukin-2(IL-2), interleukin-8 (IL-8), tumor necrosis factor-α(TNF-α) patients with chronic bronchitis and clinical efficacy. Methods Sixty patients with chronic bronchitis were randomly divided randomly into Chinese medicine acupuncture group (observation group) and the control group, with 30 cases in each group. Patientsin in the control group received an anti-inflammatory, cough and phlegm, spasmolysis and asthma. Those in observation group received acupuncture treatment in Chinese medicine on the basis of the control group. 30 days after treatment, clinical cure rate and lerel of serum inflammatory mediators IL-2, IL-8 and TNF-α of two groups were compored. Results Total effective rate (94.6%) of observation group was significantly higher than that (74.6%) of the control group (P<0.05) serum IL-2 of Observation group was significantly higher than that of control group (P<0.05) and IL-8, TNF-α level was significantly lower than control group (P<0.05) and the difference was statistically significant. Conclusion Chinese medicine acupuncture treatment can effectively reduce inflammatory reaction and clinical symptoms in patients with chronic bronchitis,improve the body's immune regulating force.
keywords:Chronic bronchitis  Acupuncture  Inflammatory mediators  Curative effect
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