慢性阻塞性肺疾病患者营养状态评价研究
投稿时间:2015-05-06  修订日期:2015-05-10  点此下载全文
引用本文:刘广杰,胥杰,罗秀芳.慢性阻塞性肺疾病患者营养状态评价研究[J].医学研究杂志,2015,44(7):47-49
DOI: 10.11969/j.issn.1673-548X.2015.07.014
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作者单位
刘广杰 100730 首都医科大学附属北京同仁医院呼吸内科 
胥杰 100730 首都医科大学附属北京同仁医院呼吸内科 
罗秀芳 100730 首都医科大学附属北京同仁医院呼吸内科 
基金项目:教育部留学回国人员科研启动基金资助项目(2005546)
中文摘要:目的 探究慢性阻塞性肺疾病、慢性支气管炎患者营养状态的改变,探讨GOLD分组各组中慢性阻塞性肺疾病患者的营养状态。方法 观察稳定期慢性阻塞性肺疾病患者40例,病情程度分别处于GOLD分组的A 、B、C、D组,每组患者10例。另外选取慢性支气管炎患者20例,健康人对照20例。分别检测体重指数(BMI)、肱三头肌皮皱(TSF)、血浆白蛋白水平(ALB),评估其营养状态。结果 慢性阻塞性肺疾病患者与健康对照组营养状态指标如下:BMI 分别为21.3±4.0kg/m2和24.7±3.7kg/m2, 差异有统计学意义(P<0.01);TSF分别为10.3±4.4mm和13.0±4.4mm,差异有统计学意义(P<0.05);ALB分别为34.4±5.3g/L和39.5±6.7g/L,差异有统计学意义(P<0.01);慢性阻塞性肺疾病患者依据GOLD分组为A、B、C、D组,依据肺功能将其分为A+B组、C+D组,两组检测指标BMI分别为22.1±3.5kg/m2和19.9±4.3kg/m2,差异有统计学意义(P<0.05); TSF分别为12.9±4.4mm和7.7±2.4mm,差异有统计学意义(P<0.01);ALB分别为36.5±5.4g/L和32.3±4.5g/L,差异有统计学意义(P<0.01);慢性支气管炎组BMI、TSF及ALB的检测指标与对照组相比,差异无统计学意义(P>0.01)。结论 慢性阻塞性肺疾病患者的BMI、TSF、ALB较健康对照组显著降低,存在营养状态不良。GOLD分组中C组与D组的的营养状态较A组与B组差。在临床工作中,GOLD分组中C、D组患者需更加关注其营养状态并给予相应措施。
中文关键词:慢性阻塞性肺疾病  GOLD分组  营养
 
Study on the Nutrition Status in Patients with COPD
Abstract:Objective To investigate the parameters of nutrition status in the patients with COPD and study the difference nutrition status among COPD GOLD classification including A, B,C and D. Methods According to the global initiative for chronic obstructive lung disease (GOLD) criteria, we classified the COPD outpatients into A, B, C, D group, with 10 cases in each group, 20 cases healthy people as control group as well as 20 patients with chronic bronchitis. Body mass index (BMI) , triceps skin-fold thickness(TSF),serum albumin(ALB) were measured in each person. Results BMI was significantly lower in COPD group than health control group (21.3±4.0kg/m2 vs 24.7±3.7kg/m2, P<0.01); TSF was significantly reduced in COPD group than the control group (10.3±4.4mm vs 13.0±4.4mm, P<0.05); ALB in COPD group was significant decreased than the control group (34.4±5.3g/L vs 39.5±6.7g/L, P<0.01). Moreover, there were significantly differences in the nutrition status among COPD groups. BMI in the group of(C+D) was significantly lower compared with the group of (A+B) (19.9±4.3kg/m2 vs 22.1±3.5kg/m2, P<0.05). TSF was significantly decreased in the group of (C+D) than the group of (A+B)(7.7±2.4mm vs 12.9±4.4mm, P<0.01). Compared with the group of (A+B), ALB was also significantly reduced in the group of (C+D)(32.3±4.5g/L vs 36.5±5.4g/L, P<0.01).Conclusion The parameters of BMI, TSF, ALB are significantly reduced in the patients with COPD. Severe COPD easily develops malnutrition. According to COPD GOLD classification, the nutrition status is worse in the group of (C+D) than in the group of (A+B). It is worthy to pay attention to the nutrition status of COPD patients, and give appreciate therapy for patients with COPD.
keywords:COPD  GOLD classification  Nutrition
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