| 骨折患者术前凝血及纤溶功能对术后血栓栓塞症的风险预测 |
| 投稿时间：2014-09-09 修订日期：2014-10-08 点此下载全文 |
| 引用本文：胡定祥,林达强,唐天生,何芳.骨折患者术前凝血及纤溶功能对术后血栓栓塞症的风险预测[J].医学研究杂志,2015,44(7):162-164 |
| DOI：
10.11969/j.issn.1673-548X.2015.07.046 |
| 摘要点击次数: 1019 |
| 全文下载次数: 782 |
|
|
| 中文摘要:目的 探讨能预测骨折患者术后发生血栓栓塞症的凝血与纤溶指标。方法 收集2012年2月~2013年12月入笔者医院行骨折手术并术前行螺旋CT、彩色多普勒超声或血管造影等影像学检查的患者321例,其中发生静脉血栓栓塞症的患者13例设为A组,无静脉血栓栓塞症的患者308例设为B组,选取同期健康体检人员150例作对照组,分别检测凝血及纤溶系统各指标。结果 与对照组相比,A组与B组的TT值比较,差异无统计学意义(P>0.05);PLT、FIB、AT-Ⅲ值显著升高且A组高于B组(P<0.05),但其值仍处于或接近正常范围;APTT与PT值显著降低且A组低于B组(P<0.05),但其值也仍处于或接近正常范围;D-D值进行性升高,A组显著高于B组且A组显著超出正常参考范围(P<0.001)。结论 凝血及纤溶功能各项指标中,PLT、APTT、PT、TT、FIB及AT-Ⅲ对术后发生血栓栓塞症的风险预测不足,只有D-D值可能对骨折术后静脉血栓栓塞症的发生具有良好预测作用。 |
| 中文关键词:骨折 凝血功能 血栓栓塞症 |
| |
| Items of Blood Coagulation and Fibrinolysis in Preoperative Patients with Fracture on Risk Prediction of Vein Thrombosis |
|
|
| Abstract:Objective To investigate the items of blood coagulation and fibrinolysis in preoperative patients with fracture on risk prediction of vein thrombosis predictive. Methods A total of 321 patients suffered fractures with spiral CT, color Doppler ultrasonography and angiography imaging examination before fracture surgery were retrospectively analyzed from February 2012 to December 2013, of whom (13 cases) underwent vein thrombosis set to group A , of what (308 cases) not underwent vein thrombosis set to group B and the same period in healthy volunteers 150 selected as control group. The items of blood coagulation and fibrinolysis were detected. Results Compared with the control group, TT values of group A and group B had no significant difference (P>0.05). PLT, FIB, AT-Ⅲ were significantly higher in group A than in group B (P<0.05), but its values still at or near the normal range. APTT and PT values were significantly lower in group A than in group B (P<0.05), but its value was also at or near the normal range. DD value was increased,and group A was significantly higher than group B and group A was significantly beyond the normal reference range (P<0.001). Conclusion PLT, APTT, PT, TT, FIB and AT-Ⅲ were deficiency for predication the risk of vein thrombosis of patients with fractures, only DD may can finely predict the risk of vein thrombosis postoperative of patients with fractures. |
| keywords:Fracture Coagulation Thromboembolism |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
