| CT引导下经皮芯针活检检测骨病变的影响因素分析 |
| 投稿时间：2014-12-19 修订日期：2014-12-24 点此下载全文 |
| 引用本文：王轶骏,费青,张蕾.CT引导下经皮芯针活检检测骨病变的影响因素分析[J].医学研究杂志,2015,44(8):129-132 |
| DOI：
10.11969/j.issn.1673-548X.2015.08.037 |
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| 基金项目:上海市浦东新区卫生和计划生育委员会科技基金资助项目(面上项目)(PW2013A-4) |
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| 中文摘要:目的 探讨CT引导下经皮芯针活检(core needle biopsy,CNB)检测骨病变的影响因素。 方法 回顾性分析笔者医院进行CT引导下经皮CNB检测骨病变的患者124例,对患者年龄、性别、病变部位、病变类型、组织样本大小和病变直径进行单因素分析;对单因素分析结果中有意义的病变类型和病变直径这两个因素进行Logistic多因素分析用该方法检测骨病变的影响因素。 结果 单因素分析结果显示病变类型和病变直径是CT引导下经皮CNB检测骨病变的两个影响因素。溶骨性骨病变(检出率94.5%)较硬化性骨病变(检出率94.5%)更易被检出(P<0.05),其被检出的可能性约为硬化性骨病变的10倍(OR=10.37,95% CI:4.21~35.69);骨病变直径≥3cm(检出率95.1%)较病变直径<3cm(检出率79.2%)更易被检出(P<0.05),其被检出的可能性约为病变直径<3cm的5倍(OR=5.02,95% CI:1.78~18.29)。 结论 骨病变类型和病变直径是CT引导下经皮CNB检测骨病变的影响因素,溶骨性骨病变和病变直径≥3cm具有较高的检出率。 |
| 中文关键词:骨病变 芯针活检 溶骨性骨病变 硬化性骨病变 |
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| Factors Influencing Diagnostic Yield of CT-guided Percutaneous Core Needle Biopsy for Bone Lesions |
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| Abstract:Objective To evaluate the factors influencing diagnostic yield of computed tomography (CT)-guided percutaneous core needle biopsy (CNB) for bone lesions. Methods consecutive CT-guided CNB procedures were performed in 124 patients. The variables analysed were age, sex, lesion location, lesion type, specimen size and lesion size. The factors influencing diagnostic yield of CT-guided percutaneous CNB for bone lesions were determined by multivariate analysis of variables. Results Lesion type and lesion size were determining factors in diagnostic yield. Diagnostic yield was 94.5% for lytic bone lesions that was 10 times more likely than a sclerotic bone lesion 61.9% (P<0.05, OR=10.37, 95% CI:4.21-35.69). Diagnostic yield was 95.1 for lesion size ≥3cm that was 5 times more likely than lesion size <3cm (P<0.05, OR=5.02,95% CI:1.78-18.29). Conclusion Lesion type and lesion size are determining factors in diagnostic yield. The higher diagnostic yield is correlated with lytic lesion and lesion size ≥3cm. |
| keywords:Bone lesion Core needle biopsy (CNB) Lytic bone lesion Sclerotic bone lesion |
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