| 补肾活血祛湿除痹法联合玻璃酸钠治疗膝骨性关节炎的临床研究 |
| 投稿时间：2014-12-26 修订日期：2015-01-26 点此下载全文 |
| 引用本文：李刚,杨勇,胡仕其,黄品强,刘智,高春洪.补肾活血祛湿除痹法联合玻璃酸钠治疗膝骨性关节炎的临床研究[J].医学研究杂志,2015,44(9):134-138 |
| DOI：
10.11969/j.issn.1673-548X.2015.09.038 |
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| 中文摘要:目的 观察补肾活血祛湿除痹法联合玻璃酸钠关节腔内注射治疗膝骨性关节炎的临床疗效。 方法 2013年4月~2014年9月,将120例膝骨性关节炎病例随机分为A、B、C 3组各40例。A组口服补肾活血祛湿除痹法方剂,同时膝关节腔内注射玻璃酸钠。B组口服补肾活血祛湿除痹法方剂。C组膝关节腔内注射玻璃酸钠。选择治疗前、治疗5周及治疗后3个月为时间观察点,应用视觉模拟评分、膝关节活动度、KSS稳定性评分、Lequesne肿胀评分及WOMAC评分评价治疗前后关节疼痛、活动度、稳定性、肿胀情况及综合功能等方面的区别。 结果 A组40例,B组38例,C组37例成功完成治疗及随访。补肾活血祛湿除痹法联合玻璃酸钠治疗膝骨性关节炎能长期有效的减轻膝关节疼痛,改善膝关节活动度,消除肿胀及改善膝关节综合功能;补肾活血祛湿除痹法方剂在上述方面也能取得较好的效果,停药后能维持;单纯玻璃酸钠能取得一定的效果,但停药后在减轻膝关节疼痛,改善膝关节活动度,消除肿胀等方面容易出现反跳。3组对提高膝关节稳定性方面无效。 结论 补肾活血祛湿除痹法联合玻璃酸钠治疗膝骨性关节炎是一种简便实用且有效的保守治疗方法。 |
| 中文关键词:补肾活血法 膝骨性关节炎 玻璃酸钠 关节腔注射 |
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| Clinical Research of Bushen Huoxue Qushi Chubi Decoction Combined with Hyaluronic Acid in the Treatment of Knee Osteoarthritis |
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| Abstract:Objective To observe the clinical therapeutic effect of Bushen Huoxue Qushi Chubi decoction combined with intra-articular injection of hyaluronic acid in the treatment of knee osteoarthritis. Methods From April 2013 to September 2014, 120 cases of knee osteoarthritis were randomly divided into A, B, C three groups of 40 cases. Patients in group A were treated by Bushen Huoxue Qushi Chubi decoction. At the same time, the knee joint cavity injection of hyaluronic acid. Those in group B were treated by Bushen Huoxue Qushi Chubi decoction. Those in group C were treated by intra-articular injection of hyaluronic acid. Before treatment, 5 weeks and 3 months of treatment were shosen as the observation time points.Visual analogue score, range of motion, KSS stability score, Lequesne swelling score and WOMAC score were used to evaluate the differences between joint pain, activity, stability, swelling and the comprehensive function before and after the treatment. Results Group A of 40 cases, 38 cases in group B, group C of 37 patients successfully completed the treatment and follow-up. Bushen Huoxue Qushi Chubi decoction combined with hyaluronic acid in the treatment of knee osteoarthritis can effectively relieve the pain of knee joint, improve the activity of knee joint, eliminate swelling and improving the comprehensive function of knee joint in long term; Bushen Huoxue Qushi Chubi decoction can also achieve good results in the above aspects, which can maintain after stopping drug. Pure hyaluronic acid can achieve a certain effect, but after stopping drug in the aspect of reducing knee pain, improving the activity of knee joint and eliminating swelling,it was easy to rebound. The three groups showed invalid effect to improve the stability of the knee joint. Conclusion Bushen Huoxue Qushi Chubi decoction combined with intra-articular injection of hyaluronic acid in the treatment of knee osteoarthritis is a simple, practical and effective method of conservative treatment. |
| keywords:Bushen Huoxue decoction Knee osteoarthritis Hyaluronic acid Intra-articular injection |
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