| 宁波市过敏患者过敏原分析 |
| 投稿时间：2014-11-23 修订日期：2014-12-05 点此下载全文 |
| 引用本文：张恩,李霞,王刚,王峰.宁波市过敏患者过敏原分析[J].医学研究杂志,2015,44(9):146-149 |
| DOI：
10.11969/j.issn.1673-548X.2015.09.041 |
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| 中文摘要:目的 了解宁波市过敏性疾病的过敏原分布情况及季节、年龄等影响因素。 方法 将1431例患者分成3组(A组:<18岁;B组:18~60岁;C组:>60岁),采用德国Mediwiss公司生产的Allergy Screen免疫印迹试验系统,检测血清中19种常见特异性过敏原IgE抗体(SIgE)和总IgE抗体(TIgE)。 结果 1431例过敏患者过敏原阳性率为77.78%。A组前3位的SIgE分别是户尘螨(40.07%)、牛奶(10.75%)、虾(4.85%),B组前3位的SIgE分别是户尘螨(24.91%)、柏榆(7.12%)、蟑螂(7.12%),C组前3位的SIgE分别是户尘螨(12.81%)、苋(8.54%)、矮豚草(7.47%);过敏原阳性患者前3位的疾病分别是急、慢性荨麻疹患者(23.09%)、肺炎(18.24%)、皮炎(14.11%);过敏性患者春季过敏原阳性率为68.16%,夏季过敏原阳性率为84.78%。 结论 本地区过敏患者过敏原阳性率较高,不同年龄、不同类型的过敏患者在不同季节过敏原可能不同,可根据疾病类型、年龄、季节选择过敏原检测范围,了解致敏情况,针对性的防治过敏性疾病。 |
| 中文关键词:过敏性疾病 过敏原 总IgE抗体 |
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| Analysis on Allergens of Allergic Diseases in Ningbo City |
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| Abstract:Objective To investigate the distribution of allergens in patients of allergic diseases, and find out common allergens in Ningbo. Methods Serum IgE antibodies to 19 specific allergens and total IgE concentration were quantitatively determined with immunblotassay in 1431 patients(group A <18 years, group B 18-60 years,group C >60 years). Results 72.33% positive ratio was detected among the patients.The top three SIgEs in group A were dust acarid(40.07%),milk(10.75%),shrimp(4.85%).The top three SIgEs in group B were dust acarid(24.91%),elm(7.12%)、cockroach(7.12%).The top three SIgEs in group C were dust acarid(12.81%),amaranth(8.54%),short ragweed(7.47%).The top three diseases of positive patients were urticaria(23.09%),pneumonia(18.24%),dermatitis(14.11%).Positive ratios were respectively 68.16% in spring and 84.78% in summer. Conclusion Positive ratio was high among the local patients.The allergens are different in different diseases, different seasons and different ages. It is necessary to find relevant allergens of patients and provide foundation of the prevention and treatment of allergic dermatitis. |
| keywords:Allergic diseases Allergen Total IgE antibody |
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