| 尿电解质肌酐比、总蛋白肌酐比在体检和高血压人群中的临床应用 |
| 投稿时间：2015-01-05 修订日期：2015-01-23 点此下载全文 |
| 引用本文：叶桂云,胡望平,池细弟,张忠源,王凯,张永平.尿电解质肌酐比、总蛋白肌酐比在体检和高血压人群中的临床应用[J].医学研究杂志,2015,44(10):144-148 |
| DOI：
10.11969/j.issn.1673-548X.2015.10.041 |
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| 中文摘要:目的 运用尿电解质肌酐比计算膳食盐,评价人群盐摄入量。探讨尿电解质肌酐比、尿蛋白肌酐比(urinary protein/creatinine ratio, TPCR)在体检和高血压患者中的应用价值。 方法 检测948例(其中842名>50岁)健康体检者,616例住院高血压患者的尿钠、尿钾、尿总蛋白和空腹血清脂类项目,计算出尿钠肌酐比,尿钾肌酐比、尿钠钾比(Na+/K+)、TPCR和血清载脂蛋白B/A1(apoB/apoA1)。 结果 948例体检者按年龄段分组比较中,尿TPCR在50~60岁年龄组与>70岁年龄组差异最明显(P=0.000);842例>50岁体检者不同性别间比较,尿盐、尿钾差异均有统计学意义(P=0.000);高血压组与体检组比较,尿TPCR、尿Na+/K+、尿盐差异有统计学意义(P=0.000);不同级别高血压的尿盐、Na+/K+及TPCR等指标均显著增高(P=0.000);616例高血压尿总蛋白与尿Na+/K+、尿Na+具有相关性;图中的尿TPCR浓度随年龄加大逐渐上升,高血压尿TPCR与尿Na+/K+均显著高于正常体检者。 结论 通过尿电解质计算膳食盐,能简便有效反映人群盐摄入量的高低。尿电解质肌酐比、尿TPCR与高血压的升级及年龄增大紧密相关。 |
| 中文关键词:尿电解质肌酐比 总蛋白肌酐比 钠钾比 高血压 膳食盐 |
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| Application of Urinary Electrolyte/Creatinine Ratio, Urinary Total Protein/Creatinine Ratio In Healthy People and Hypertensive Patients |
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| Abstract:Objective To investigate the salt intake of people by urine electrolytes/creatinine ratio calculating dietary salt and the application of urine electrolytes/creatinine ratio and urinary total protein/creatinine ratio on healthy people and hypertension. Methods Urinary sodium, urinary potassium, urine total protein and fasting serum lipids were detected in 948 (842 cases > 50 years old) healthy people and 616 hypertensive Patients, and Urinary Sodium /Creatinine Ratio(USCR), urinary potassium creatinine ratio, urinary sodium/potassium (Na+/K+), urinary protein creatinine ratio (TPCR) and apoB/apoA1 were calculated. Results Urine TPCR of 50 to 60 years group showed significant difference compared to > 70 years group by age grouping in 948 participants (P= 0.000). Urine salt and urine potassium of female showed obvious difference compared to male in 842 cases >50 years healthy people(P = 0.000). Urine TPCR, urine Na/K and urine salt were significantly highter in hypertension group than healthy group(P = 0.000). Urine salt, Na+/K+ and TPCR in different levels of hypertension were significantly difference (P = 0.000). Urine TPCR was positively correlated with urine Na+/K+ and USCR by linear correlation analysis in 616 hypertensive patients. Along the age escalating, urine TPCR increased gradually in figure, urine TPCR and urine Na+/K+ were significantly higher in hypertension than health. Conclusion Urine electrolytes/creatinine ratio is simple and effective to reflect the salt intake. Urine TPCR is closely related with hypertension upgrading and age escalating. |
| keywords:Urinary electrolyte/creatinine ratio Urinary protein/creatinine ratio Urinary Na+/K+ Hypertension Dietary sodium intake |
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