曲安奈德混悬剂辅助治疗老年多节段胸椎骨折后韧带骨化症的临床效果
投稿时间:2015-04-15  修订日期:2015-04-20  点此下载全文
引用本文:菅志飞,孙维,曹洪,杨华清.曲安奈德混悬剂辅助治疗老年多节段胸椎骨折后韧带骨化症的临床效果[J].医学研究杂志,2015,44(12):98-101
DOI: 10.11969/j.issn.1673-548X.2015.12.027
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作者单位E-mail
菅志飞 442000 十堰, 湖北医药学院附属东风总医院创伤外科  
孙维 442000 十堰, 湖北医药学院附属东风总医院创伤外科  
曹洪 442000 十堰市人民医院骨科  
杨华清 442000 十堰, 湖北医药学院附属东风总医院创伤外科 yanghuaqing69@163.com 
基金项目:湖北省教育厅基金资助项目(Q20132108)
中文摘要:目的探讨曲安奈德混悬剂辅助治疗老年多节段胸椎骨折后韧带骨化症的临床效果。方法老年多节段胸椎骨折后韧带骨化症患者88例根据抽签原则随机分为治疗组与对照组各44例,所有患者都给予胸椎骨折减压术,同时治疗组术后给予曲安奈德混悬剂辅助治疗,每周注射1次,共治疗4次。结果手术均顺利完成,且两组手术所用时间及术中出血量之间差异均无统计学意义,但在住院时间上治疗组明显比对照组少(P<0.05)。两组术前疼痛评分与JOA评分对比差异无统计学意义,不过治疗组术后第1周和术后第4周的疼痛评分明显低于对照组(P<0.05),治疗组术后第1周和术后第4周的JOA评分明显高于对照组(P<0.05)。治疗组术后4周内的伤口感染、神经根麻痹、肺部感染、假关节形成等并发症发生情况明显少于对照组(P<0.05),所有并发症经过对症处理后好转。结论曲安奈德混悬剂辅助手术治疗老年多节段胸椎骨折后韧带骨化症能有效发挥镇痛作用,促进胸椎功能的恢复,减少并发症的发生,从而有利于患者的康复。
中文关键词:曲安奈德  多节段胸椎骨折  后韧带骨化症  并发症
 
Clinical Effects of Triamcinolone Acetonide Suspension Adjuvant Therapy for Elderly Multi-segmental Thoracic Fractures Ligament Ossification.
Abstract:Objective To investigate the clinical effects of triamcinolone acetonide suspension adjuvant therapy for elderly multi-segmental thoracic fractures ligament ossification. Methods Eighty eight elderly multi-segmental thoracic fractures ligament ossification patients based on the principle of a random draw were equally divided into the treatment group and the control group. All patients were given decompression thoracic fractures, while the treatment group were given triamcinolone acetonide suspensions adjuvant therapy, 1 injection once a week for 4 times. Results All patients were successfully completed surgery. The blood loss, operative time compared difference of the two groups were not statistically significant, but the postoperative hospital stay in the treatment group were significantly less than the control group (P<0.05). The preoperative pain scores and JOA scores compared in the two groups had no significant difference, but the postoperative 1 week and 4 weeks pain scores in the treatment group were significantly lower than the control group (P<0.05), and the postoperative 1 week and 4 weeks JOA scores in the treatment group were significantly higher than the control group (P<0.05)(P<0.05). In the postoperative 4 weeks, the wound infection, nerve root palsy, lung infection, pseudarthrosis and other complications in the treatment group were significantly lower than in the control group (P<0.05). All the complications after symptomatic treatment were improved. Conclusion Triamcinolone acetonide suspension adjuvant therapy for elderly multi-segmental thoracic fractures ligament ossification can play the effective analgesic effect, promote the recovery of the thoracic spine function, reduce complications, thus it is contributes to the rehabilitation of patients.
keywords:Triamcinolone acetonide  Multi-segmental thoracic fractures  Ligament ossification  Complications
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