| 血浆渗透压和APACHEⅡ评分对心肺复苏后患者脑损伤的评估 |
| 投稿时间：2015-04-08 修订日期：2015-04-30 点此下载全文 |
| 引用本文：李乾锋,张迪,陈晓斌,吴京雷,段发亮.血浆渗透压和APACHEⅡ评分对心肺复苏后患者脑损伤的评估[J].医学研究杂志,2015,44(12):139-141 |
| DOI：
10.11969/j.issn.1673-548X.2015.12.038 |
| 摘要点击次数: 996 |
| 全文下载次数: 746 |
|
|
| 中文摘要:目的探讨心肺复苏后患者血浆渗透压和APACHEⅡ评分对脑损伤预后的研究价值。方法选取心肺复苏后患者31例,其中预后不良组18例,预后良好组13例,选取健康体检者20例为对照组,比较3组患者入院时的血浆渗透压和急性生理学与慢性健康状况Ⅱ(APACHEⅡ)评分,绘制ROC曲线,进行统计学分析。结果与对照组相比,预后不良组血浆渗透压明显升高(P<0.05),而预后良好组则无明显差异;两组患者APACHEⅡ评分均明显升高,差异有统计学意义(P<0.05)。预后不良组血浆渗透压和APACHEⅡ评分明显高于预后良好组,差异有统计学意义(P<0.05)。预后良好组血浆渗透压异常率为15.38%,预后不良组血浆渗透压异常率为66.67%(P<0.05)。血浆渗透压预测心肺复苏后患者脑损伤的曲线下面积为0.75,APACHEⅡ评分曲线下面积为0.835。心肺复苏后患者血浆渗透压与APACHEⅡ评分呈正相关(r=0.834,P<0.05)。结论心肺复苏后患者血浆渗透压升高、APACHE Ⅱ评分增大,预示脑功能预后不良,二者可以用来早期评估心肺复苏后患者脑损伤预后。 |
| 中文关键词:渗透压 急性生理学与慢性健康状况评分Ⅱ 心肺复苏 脑损伤 预后 |
| |
| Effect of Plasma Osmolality and APACHEⅡ Score on Brain Damage after Cardiopulmonary Resuscitation. |
|
|
| Abstract:Objective To explore the effects of plasma osmolality and APACHEⅡscore on brain damage after cardiopulmonary resuscitation. Methods A total of 31 patients after cardiopulmonary resuscitation were selected. The patients were divided into unfavorable prognosis group (n=18) and favorable prognosis group (n=13) according to prognosis. 20 subjects undergoing health check served as control group. The level of plasma osmolality is detected and acute physiology and chronic health evaluationⅡ(APACHEⅡ) scores were estimated in all the patients at admission. Data were analyzed and receiver operating characteristic (ROC) curves were made. Results The plasma osmolality level was significantly higher in unfavorable prognosis group than in control group (P<0.05) whereas there was no difference in favorable prognosis group. The APACHEⅡ score was significantly higher in two groups than in control group (P<0.05). The plasma osmolality level and the APACHEⅡ score were higher in unfavorable prognosis group than in favorable prognosis group (P<0.05). The abnormal rate of plasma osmolality in survival group was 15.38%, whereas it was 66.67% in death group (P<0.05). ROC curves for unfavorable prognosis of patients revealed an area under the curve of 0.75 for plasma osmolality, and 0.835 for APACHEⅡ Score. The plasma osmolality level was positively related with APACHEⅡscore in patients with brain damage after cardiopulmonary resuscitation (r=0.834, P<0.05). Conclusion The plasma osmolality and APACHEⅡ Score were increased in patients with brain damage after cardiopulmonary resuscitation which indicates poor prognosis of brain function. So the level of plasma osmolality and APACHEⅡ Score can be used to evaluate brain damage after cardiopulmonary resuscitation. |
| keywords:Osmolality APACHEⅡ score Cardiopulmonary resuscitation Brain damage Prognosis |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
