新疆乌鲁木齐维、汉族碘营养水平与甲状腺结节的相关研究
投稿时间:2015-07-03  修订日期:2015-07-10  点此下载全文
引用本文:郭艳英,王惠丽,马福慧,王新玲,艾合买提江·吐呼提,木尼拉·阿不都乃依木,热孜万古丽·乌斯曼,赵红丽,邢淑清.新疆乌鲁木齐维、汉族碘营养水平与甲状腺结节的相关研究[J].医学研究杂志,2016,45(2):58-61,67
DOI: 10.11969/j.issn.1673-548X.2016.02.016
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作者单位E-mail
郭艳英 830001 乌鲁木齐, 新疆维吾尔自治区人民医院内分泌科  
王惠丽 830001 乌鲁木齐, 新疆维吾尔自治区人民医院内分泌科  
马福慧 830001 乌鲁木齐, 新疆维吾尔自治区人民医院内分泌科  
王新玲 830001 乌鲁木齐, 新疆维吾尔自治区人民医院内分泌科 wangxinling@medmail.com.cn 
艾合买提江·吐呼提 830001 乌鲁木齐, 新疆维吾尔自治区人民医院内分泌科  
木尼拉·阿不都乃依木 830001 乌鲁木齐, 新疆维吾尔自治区人民医院内分泌科  
热孜万古丽·乌斯曼 830001 乌鲁木齐, 新疆维吾尔自治区人民医院内分泌科  
赵红丽 830001 乌鲁木齐, 新疆维吾尔自治区人民医院内分泌科  
邢淑清 830001 乌鲁木齐, 新疆维吾尔自治区人民医院内分泌科  
基金项目:新疆维吾尔自治区自然科学基金资助项目(2013211A105);新疆乌鲁木齐市天山区科学技术计划项目(20120101)
中文摘要:目的 探讨新疆乌鲁木齐维汉族碘营养状况、甲状腺结节流行情况及碘营养与甲状腺结节的相关性。方法 对乌鲁木齐地区2251名社区居民,其中维吾尔族804例,汉族1031例成人进行体格检查及问卷调查,测定尿碘,进行甲状腺B超检查。结果 11835例尿碘中位数是133.41μg/L,碘缺乏594例(32.37%),碘适量788例(42.94%),碘超足量265例(14.44%),碘过量187例(10.19%),尿碘水平汉族高于维族(Z=-2.797,P=0.005),男女差异无统计学意义(Z=-1.296,P=0.195);2甲状腺结节检出率维汉族差异无统计学意义(χ2=0.01,P=0.915);女性显著高于男性(χ2=72.86,P<0.01)。甲状腺结节检出率碘过量组高于碘适量组(P=0.020)和碘缺乏组(P=0.040),与超足量组无差别,且民族、性别内差异无统计学意义(P>0.05);3维汉、男女单发均多于多发结节,但无论民族、性别,患不同类型甲状腺结节人群的尿碘含量差异无统计学意义(P>0.05)。结论 目前乌鲁木齐维汉两族人群碘营养水平处于适宜范围。甲状腺结节发生率较低,女性多于男性,且结节发生率与尿碘梯度有关。单发结节多于多发结节,无论民族、性别,不同类型结节与尿碘水平无相关性。
中文关键词:尿碘  甲状腺结节  维吾尔族  汉族
 
Abstract:Objective To investigate iodine nutrition status and relationship with the thyroid nodule occurrence of Uighur and Han in Urumqi, Xinjiang. Methods A total of 2251 community residents were investigated, including Uighur 804, Han 1031 adults for medical examinations and questionnaires, to determine urinary iodine, thyroid B ultrasound. Results 1The average median urinary iodine of 1835 residents was 133.41μg/L. 594 subjects(32.37%) were iodine deficient, and 788 subjects(42.94%) belonged to the adequate iodine, and 265 subjects(14.44%) were more than adequate, and 187 subjects(10.19%) were iodine excessive. The Uighur was lower than the Han(Z=-2.797, P=0.005), no difference between with men and women(Z=-1.296, P=0.195). 2The nodules detection rate of two nationalities had no difference(χ2=0.01, P=0.915), and women were significantly higher than men(χ2=72.86, P<0.01).The thyroid nodules rate of iodine excess was higher than iodine sufficient(P=0.014) or deficiency group(P=0.040), and neither nationality nor gender had nodules rate difference in four groups. 3The single nodules were more than multiple nodules, but no matter nationality or gender, patients urinary iodine levels showed no difference in two nodules types respectively. Conclusion Iodine nutrition was within the appropriate range in Urumqi. Thyroid nodule prevalence rate was low and related to the level of urinary iodine. Women's thyroid nodule rate was higher than men. Solitary nodule was more than multiple nodules, and the type of nodules and urinary iodine had no correlation.
keywords:Urinary iodine  Thyroid nodule  Uighur  Han nationality
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