| 声速匹配技术评价乳腺肿物性质的研究 |
| 投稿时间：2015-07-03 修订日期：2015-07-30 点此下载全文 |
| 引用本文：方俊,阚艳敏,马琳,温玉良.声速匹配技术评价乳腺肿物性质的研究[J].医学研究杂志,2016,45(2):135-138 |
| DOI：
10.11969/j.issn.1673-548X.2016.02.035 |
| 摘要点击次数: 1090 |
| 全文下载次数: 755 |
|
|
| 中文摘要:目的 探讨声速匹配技术在乳腺肿物良恶性鉴别诊断中的临床价值。方法 121例患者共127个乳腺肿物(良性83个、恶性44个)进行声速匹配技术测定从而计算其声速,并以病理诊断结果作为金标准,构建ROC曲线确定乳腺肿物良恶性声速的临界值。按照病理诊断结果把乳腺肿物分为良恶性两组,并依据乳腺肿物深度、乳腺皮下脂肪层厚度及乳腺腺体层厚度再进行分组,分析乳腺肿物声速在不同分组中的差异。结果 良性乳腺肿物声速值为1521.00±21.02m/s,恶性乳腺肿物声速值为1572.00±22.33m/s,两者声速值比较差异有统计学意义(P<0.05);ROC曲线诊断良恶性肿物的声速临界值为1551.00m/s,ROC曲线下面积0.935,约登指数0.780,声速鉴别良恶性肿物的敏感度为86.4%,特异性为91.6%;良、恶性两组乳腺肿物的声速在乳腺不同皮下脂肪层及腺体层厚度之间的差异无统计学意义。在良性组中乳腺肿物声速在不同深度组之间存在差异,差异有统计学意义(P<0.05),在恶性组中比较,差异无统计学意义(P>0.05)。结论 声速匹配技术可为临床诊断乳腺肿物良恶性提供客观的定量依据,为超声鉴别诊断乳腺肿物良恶性提供了一项新指标;乳腺肿物的深度对肿物声速有影响。 |
| 中文关键词:乳腺肿物 声速匹配技术 声速 |
| |
|
|
|
| Abstract:Objective To evaluate the clinical value of zone speed index technique in the differential diagnosis between the benign and malignant breast neoplasm. Methods One hundred and twenty-one patients with one hundred and twenty-seven breast neoplasm(83 benign, 44 malignant) were included in the study.The zone speed index was measured when the breast neoplasm was found by the ultrasound, the sound velocity was calculated. Compared with the pathological diagnosis, the threshold of sound velocity was determined by the ROC cure. According to the pathological diagnosis, the breast neoplasm were divided into two groups, and the sound velocity of the breast tumor were analyzed according to the depth of the breast neoplasm, breast subcutaneous fat layer thickness and the thickness of mammary glands. Results There was significant difference of sound velocity between the benign and malignant breast neoplasm(P<0.05). Sound velocity of benign breast neoplasm was 1521.00±21.02m/s, sound velocity of malignant breast neoplasm was 1572.00±22.33m/s. 1551.00m/s was the threshold of sound velocity determined by the ROC cure. The area of ROC cure was 0.935, Youden index was 0.82, sensitivity was 86.4%, and specificity was 91.6%. Sound velocity was no different between different breast subcutaneous fat layer thickness and thickness of mammary glands. There was significant difference between sound velocity in different depth in the benign group(P<0.05). There was no significant difference between sound velocity in different depth in the malignant group(P>0.05). Conclusion The zone speed index technique could be used to provide objective quantitative proof for breast neoplasm clinical diagnosis, the threshold of sound velocity could be used to provide a new indicator in the differential diagnosis of breast neoplasm. The depth of the breast neoplasm have an effect on the sound velocity. |
| keywords:Breast neoplasm Zone speed index technique Sound velocity |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
