| 综合ICU多重耐药产气肠杆菌流行特点分析 |
| 投稿时间：2015-07-20 修订日期：2015-07-23 点此下载全文 |
| 引用本文：易玲娴,张长春,易勇,贾晓君,张淑敏,高洁,王嵩,姜生茂.综合ICU多重耐药产气肠杆菌流行特点分析[J].医学研究杂志,2016,45(3):38-40 |
| DOI：
10.11969/j.issn.1673-548X.2016.03.011 |
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| 基金项目:全军"十二五"课题(面上项目)(CWS11J174) |
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| 中文摘要:目的 了解笔者医院综合ICU病房多重耐药产气肠杆菌的流行特点.方法 收集笔者医院2014年5月1日~7月30日综合ICU病房内检出产气肠杆菌的患者,统计其相关临床资料,并对检出菌株进行药敏分析.结果 24例患者共检出33株产气肠杆菌,其主要来源为呼吸道标本,占72.7%(24/33).其中多重耐药菌株(multi-drug resistant,MDR)检出32株,占97.0%,广泛耐药(extensive-drug resistant, EDR)菌株检出7株,占21.2%.产气肠杆菌除对替加环素全部敏感外,对喹诺酮类、氨基糖苷类、β内酰胺复合制剂及β-内酰胺类抗生素的耐药率分别达到97.0%、78.8%、93.9%及90.9%.对碳青酶烯类抗生素亚胺培南、厄他培南及美罗培南的耐药率分别达到93.9%、90.9%和100%.结论 多重耐药产气肠杆菌对常用抗生素均具有很高的耐药率,临床工作者应予以重视并采取积极措施降低其耐药率. |
| 中文关键词:肠杆菌属 产气肠杆菌 耐药性 |
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| Analysis on Epidemiological Characterization of Multi-drug Resistant Enterobater Aerogens in General ICU. |
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| Abstract:Objective To investigate the epidemiological characterization of multi-drug resistant(MDR)Enterobater aerogens in general ICU. Methods General ICU patients, whose secreta were isolated Enterobater aerogenes, were analyzed from 1st May to 30th July in 2014. Then, their clinical data and drug resistance was analyzed. Results Totally 33 strains Enterobater aerogenes were isolated from 24 cases patients (24/33). The main source of the isolates was respiratory tract specimen, accounting for 72.7%. MDR was detected 32 strains, accounting for 97.0%. EDR was detected 7 strains, accounting for 21.2%. Enterobater aerogenes was sensitive to tigecycline, overall. But, most of Enterobater aerogenes was resistant to Quinolones, Aminoglycosides ,β-lactam compound preparation and β-lactam antibiotic, respectively 97.0%, 78.8%, 93.9% and 90.9%. And, the drug-resistant ratio of Imipenem, Ertapenam and Meropenem, which were carbapenem antibiotic, were 93.9%, 90.9% and 100%, respectively. Conclusion MDR Enterobater aerogenes was high drug resistant to common antibiotics. Doctor should pay attention and take effective measures to decrease the resistant strains. |
| keywords:Enterobacter Enterobater aerogenes Antibiotic resistance |
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