| 铁蛋白和纤维蛋白原在噬血细胞综合征疗效评价中的意义 |
| 投稿时间：2015-07-30 修订日期：2015-08-18 点此下载全文 |
| 引用本文：李佩章,王英,黄玲莎,朱波,劳明,赵惠柳,谭晓虹.铁蛋白和纤维蛋白原在噬血细胞综合征疗效评价中的意义[J].医学研究杂志,2016,45(3):58-60 |
| DOI：
10.11969/j.issn.1673-548X.2016.03.016 |
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| 基金项目:广西壮族自治区卫生厅科研基金资助项目(Z2013421) |
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| 中文摘要:目的 探讨血清铁蛋白和纤维蛋白原在评价噬血细胞综合征疗效中的意义.方法 30例健康体检者为对照组,回顾性将40例确诊噬血细胞综合征患者按照转归分为存活组和死亡组,检测并分析治疗前、后血清铁蛋白和纤维蛋白原水平变化.结果 对照组和噬血细胞综合征组铁蛋白、纤维蛋白原差异有统计学意义(P=0.000,P=0.001);存活组和死亡组患者血清铁蛋白、纤维蛋白原在治疗前后差异有统计学意义(存活组分别为P= 0.001、P= 0.000,死亡组分别为P= 0.006、P=0.000).结论 血清铁蛋白和纤维蛋白原是评价噬血细胞综合征疗效的重要指标. |
| 中文关键词:噬血细胞综合征 血清铁蛋白 纤维蛋白原 治疗 |
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| Clinical Significance of Serum Ferritin and Fibrinogen in Evaluation of Treatment Response in Hemophagocytic Syndrome. |
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| Abstract:Objective To investigate the clinical significance of serum ferritin and fibrinogen in evaluation of treatment response in hemophagocytic syndrome. Methods Thirty healthy people in normal group were established as control. 40 patients didgnosed as hemophagocytic syndrome were divided into survival group and death group according to their therapeutic results,detecting and comparing serum ferritin and fibrinogen before and after treatment. Results The variance of serum ferritin and fibrinogen levels were statistically significant in comparison with results of before and after treatment in two groups(survival group P=0.001,P=0.000; death group P=0.006,P=0.000). Conclusion The serum ferritin and fibrinogen might be useful markers in evaluation of the effiancy of treatment in patients with hemophagocytic syndrome. |
| keywords:Hemophagocytic syndrome Serum ferritin Fibrinogen Treatment |
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