| 降钙素原联合C反应蛋白检测在儿科院内感染中的应用 |
| 投稿时间：2015-10-16 修订日期：2015-11-25 点此下载全文 |
| 引用本文：吴丽敏,汪珍珍,张海燕.降钙素原联合C反应蛋白检测在儿科院内感染中的应用[J].医学研究杂志,2016,45(7):153-155,166 |
| DOI：
10.11969/j.issn.1673-548X.2016.07.041 |
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| 中文摘要:目的 探讨联合检测降钙素原（PCT）和C反应蛋白（CRP）对儿科院内感染病原体和严重程度的临床价值。方法 回顾性分析笔者医院儿科病房2013年7月～2015年7月72例院内感染的患儿，检测PCT、CRP及两者联合对细菌及病毒感染的效度。结果 PCT对细菌感染的敏感度及特异性均高于CRP，但两者联合可以提高对细菌感染的特异性。PCT联合CRP的敏感度为61.53%，特异性为95.65%，阳性预测值为88.89%，阴性预测值为81.48%。脓毒症院内感染患儿PCT及CRP较非脓毒症明显升高（P<0.01）。结论 PCT及CRP联合检测对院内细菌感染的特异性高，脓毒症时PCT及CRP明显升高。 |
| 中文关键词:降钙素原|C反应蛋白|院内感染|脓毒症 |
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| Application of Serum Procalcitonin Combined C-reactive Protein in Nosocomial Infection in Paediatrics Admissions |
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| Abstract:Objective To discuss the clinical value of serum procalcitonin(PCT) combining C-reactive protein(CRP) in pathogenic agent and degree of infection in nosocomial infection in paediatrics admissions. Methods We collected the cases of 72 patients with final diagnosis with nosocomial infection in paediatrics admissions from July 2013 to July 2015. Serum PCT, CRP were determined. The counts were compared in predictiving bacterial or virus infection. Results PCT for the diagnosis of bacterial infections had a higher sensitivity and specificity than CRP. The specificity can be increased when PCT combined with CRP,for which the sensitivity was 61.53%,the specificity was 95.65%,the positive predictive was 88.89%,the negative predictive was 81.48%.PCT and CRP were significantly higher in sepsis than non-sepsis(P<0.01). Conclusion PCT combined with CRP could serve a high specificity for bacterial infection in nosocomial infection.PCT and CRP would increase obriously in sepsis. |
| keywords:Procalcitonin|C-reactive protein|Nosocomial infection|Sepsis |
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