| 血小板淋巴细胞比率与急性冠脉综合征的相关性分析 |
| 投稿时间：2016-01-15 修订日期：2016-02-17 点此下载全文 |
| 引用本文：方钊,蒋学俊,陶波,刘浙波,王建铭,鲁明.血小板淋巴细胞比率与急性冠脉综合征的相关性分析[J].医学研究杂志,2016,45(9):48-51 |
| DOI：
10.11969/j.issn.1673-548X.2016.09.013 |
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| 基金项目:国家自然科学基金资助项目（81170307） |
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| 中文摘要:目的 探讨血清血小板/淋巴细胞比值与急性冠脉综合征的相关性。方法 冠心病的患者263例，其中不稳定型心绞痛（UA）组患者127例和急性心肌梗死（AMI）组136例。另取同一时期冠脉造影正常的住院患者53例为对照组。检测血小板及淋巴细胞计数，并计算PLR，比较3组临床资料、生化指标、炎性指标及PLR的差异。结果 UA组、MI组白细胞、中性粒细胞、淋巴细胞、PLR与对照组比较差异有统计学意义（P<0.05）；MI组白细胞、中性粒细胞、血小板、PLR与UA组相比差异有统计学意义（P<0.05）。Logistic回归分析表明年龄、吸烟、性别、PLT、PLR是UA的独立危险因素，血小板、PLR是MI的独立危险因素。结论 对照组、UA组、MI组之间PLR水平均有差异，PLR值随病变程度越重越高，高PLR水平可能是ACS的危险因素。 |
| 中文关键词:血小板淋巴细胞比值 急性冠脉综合征 相关性 |
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| Relationship between Platelet to Lymphocyte Ratio and Clinical Characteristics of Acute Coronary Syndrome |
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| Abstract:Objective To predict the association between platelet to lymphocyte ratio (PLR) and acute coronary syndrome. Methods Two hundred and sixty-three cases of coronary heart disease patients were enrolled in the stady, including 127 cases of unstable angina (UA) patients and 136 cases of acute myocardial infarction (AMI) patients.In the same period,53 cases of coronary angiography negative patients were taken as the control group. Platelet and lymphocyte count was detected and PLR was calculated. Clinical data, biochemical indicators, inflammatory markers and PLR with coronary artery disease of three groups were compared. Results Compared with the control group, white blood cells, neutrophils, lymphocytes, PLR in UA group and MI group was increased, and the difference was statistically significant (P<0.05). Compared with the UA group, white blood cells, neutrophils, platelets, PLR in MI group was increased,and the difference was statistically significant (P<0.05). Multivariate logistic regression model showed that age, smoking, sex, PLT, PLR were an independent risk factor for the UA, and platelets, PLR were an independent risk factor of MI. Conclusion The PLR level was insearsed in the control group,UA group and MI group PLR. High PLR levels may be a risk factor for ACS. |
| keywords:Platelet lymphocyte ratio Acute coronary syndrome Correlation |
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