磁共振扩散加权成像联合动态增强对乳腺病变的诊疗实效性评价
投稿时间:2016-03-16  修订日期:2016-05-05  点此下载全文
引用本文:陈博.磁共振扩散加权成像联合动态增强对乳腺病变的诊疗实效性评价[J].医学研究杂志,2016,45(12):138-141
DOI: 10.11969/j.issn.1673-548X.2016.12.037
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陈博 310022 杭州, 浙江省肿瘤医院放射科 huhongying00@163.com 
中文摘要:目的 探究磁共振扩散加权成像联合动态增强对乳腺病变的诊疗实效性。方法 选取2012年12月~2015年12月在笔者医院进行治疗的乳腺病变患者111例118个病灶,分别同时进行动态增强扫描(A组)和磁共振扩散加权成像检查(B组)及联合检测(C组),对其形态学、血流动力学等进行分析。结果 肿块性病变中,肿块边缘、毛刺征、ADC值中差异有统计学意义(P<0.05);边缘不光滑、有毛刺、内部增强不均匀、廓清型TIC曲线为有显著意义恶性征象;形状不规则、平台型曲线有恶性倾向但不显著。非肿块性病变中,良恶性病变中TIC差异有统计学意义(P<0.05);廓清型TIC曲线为恶性征象;平台型曲线有恶性倾向但差异无统计学意义(P>0.05)。C组ROC曲线下面积值均数>0.9,明显高于单纯方法的B、C组,故诊断效能最高,差异有统计学意义(P<0.05)。肿块性病变中,敏感度为80.3%(41/51),特异性为75.9%(22/29),准确性为78.8%(63/80);非肿块性病变中,敏感度为80.0%(20/25),特异性为76.9%(10/13),准确性为78.9%(30/38),差异无统计学意义(P>0.05)。结论 磁共振扩散加权成像联合动态增强对乳腺病变的诊疗特异性强敏感度高,应在临床推广使用。
中文关键词:磁共振扩散加权成像  动态增强  乳腺病变
 
Evaluation of Diagnostic and Therapeutic Effect of Magnetic Resonance Diffusion Weighted Imaging Combined with Dynamic Contrast Enhancement in Breast Lesions
Abstract:Objective To explore the effectiveness of magnetic resonance diffusion weighted imaging combined with dynamic enhancement in the diagnosis and treatment of breast lesions.Methods From December 2012 to December 2015 for treatment of 111 cases of breast lesions in patients with 118 lesions in our hospital were carried out at the same time, dynamic enhanced scan (group A) and diffusion weighted magnetic resonance imaging (B) and joint detection (C group), the morphology, blood flow mechanics analysis.Results The lesions, tumor margin, Mao Cizheng and ADC value had statistical significance in difference (P<0.05); the edge is not smooth, burr, uneven clearance, internal enhancement type TIC curve for the significant signs of malignancy; platform type curve of irregular shape and evil tendency but not significant. Non tumorous lesions, benign and malignant lesions was statistically significant TIC difference (P<0.05); TIC curves for clearance of malignant signs; platform type curve has malignant tendency but no significant level (P>0.05). C group ROC area under the curve was 0.9, significantly higher than the simple method of B, C group, it was the highest diagnostic efficacy, the difference was statistically significant (P<0.05). Mass lesions, the sensitivity was 80.3% (41/51), the specificity was 75.9%(22/29), the accuracy was 78.8%(63/80); non tumorous lesions, the sensitivity was 80.0% (20/25), specificity was 76.9% (10/13), the accuracy was 78.9% (30/38). The difference was not statistically significant (P>0.05).Conclusion Magnetic resonance diffusion weighted imaging combined with dynamic enhancement in the diagnosis and treatment of breast lesions is highly sensitive and should be used in clinical application.
keywords:Magnetic resonance diffusion weighted imaging  Dynamic enhancement  Breast lesions
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