| 血清β-hCG、CK联合子宫内膜厚度对早期异位妊娠的鉴别诊断价值 |
| 投稿时间：2016-05-05 修订日期：2016-05-11 点此下载全文 |
| 引用本文：孟亚萍,鲍正娟.血清β-hCG、CK联合子宫内膜厚度对早期异位妊娠的鉴别诊断价值[J].医学研究杂志,2016,45(12):147-149 |
| DOI：
10.11969/j.issn.1673-548X.2016.12.040 |
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| 中文摘要:目的 探讨血清人绒毛膜促性腺激素（β-HCG）、肌酸激酶（CK）联合子宫内膜厚度对早期异位妊娠的鉴别诊断价值。方法 测定108例早期异位妊娠患者（异位妊娠组）、108例宫内早孕患者（宫内早孕组）的血清β-HCG、CK水平，测量子宫内膜厚度，比较两组患者、不同孕周各检测指标的水平，分析单项及联合检测对异位妊娠的鉴别价值。结果 与宫内早孕组比较，异位妊娠组血清β-HCG、子宫内膜厚度显著降低，CK显著升高（P<0.05）；与孕周≤7周患者比较，孕周>7周患者血清CK显著升高（P<0.05）；不同孕周患者血清β-HCG、子宫内膜厚度比较，差异无统计学意义（P>0.05）；各指标联合检测的敏感度、特异性及诊断符合率分别为82.4%、93.5%、88.0%，明显高于β-HCG、CK、子宫内膜厚度任一单项检测（P<0.05）。结论 血清β-HCG、CK、子宫内膜厚度与早期异位妊娠密切相关，联合检测对于明确诊断以及治疗方案的选择具有一定指导意义。 |
| 中文关键词:异位妊娠 人绒毛膜促性腺激素 肌酸激酶 子宫内膜厚度 鉴别诊断 |
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| Differential Diagnosis Value of Combination Detection of Serum β-hCG,CK and Endometrial Thickness in Early Ectopic Pregnancy |
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| Abstract:Objective To explore the differential diagnosis value of combination detection of serum β-hCG, CK and endometrial thickness in early ectopic pregnancy.Methods The levels of serum β-hCG, CK were detected and endometrial thickness was measured in 108 patients with early ectopic pregnancy(ectopic pregnancy group), 108 cases of early intrauterine pregnancy(early intrauterine pregnancy group). The level of each indicators between two groups, different gestational age were compared, and differential diagnosis value of ectopic pregnancy by individual and combined detection was analyzed.Results Compared with early intrauterine pregnancy group, the level of serumβ-hCG, endometrial thickness decreased significantly, and the level of CK increased significantly in ectopic pregnancy group (P<0.05). Compared with patients with gestational age ≤ 7 weeks, the level of serum CK was significantly increased in patients with gestational age>7 weeks(P<0.05). There was no statistically significant difference on serumβ-hCG, endometrial thickness between different gestational age patients (P>0.05). The sensitivity, specificity and diagnose accordance rate of combined detection of three indicators were 82.4%, 93.5%, 88.0%, which were significantly higher than any of indicator alone (P<0.05).Conclusion Serum β-hCG, CK and endometrial thickness is closely related to the early ectopic pregnancy. Combined detection has certain guiding significance for diagnosis and choice of therapeutic regimen. |
| keywords:Ectopic pregnancy β-HCG CK Endometrial thickness Differential diagnosis |
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