| 痰瘀互结型多囊卵巢综合征伴高雄激素血症患者的临床特征分析 |
| 投稿时间：2016-06-15 修订日期：2016-06-23 点此下载全文 |
| 引用本文：张美微,侯丽辉,刘颖华.痰瘀互结型多囊卵巢综合征伴高雄激素血症患者的临床特征分析[J].医学研究杂志,2017,46(2):40-42 |
| DOI：
10.11969/j.issn.1673-548X.2017.02.012 |
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| 基金项目:国家重大科技专项基金资助项目——中医公益性行业专项课题（201207001）；国家中医药管理局国家中医临床研究基地业务建设科研专项基金资助项目（JDZX2012039）；国家中医药管理局全国名老中医药专家传承工作室建设项目 |
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| 中文摘要:目的 通过比较不同水平雄激素状态下痰瘀互结型PCOS的临床及生化特征，探索出痰瘀互结型PCOS伴高雄激素血症患者的临床特征，为疾病的个性化治疗和远期并发症的预防提供依据。方法 收集2015年5月~2016年5月黑龙江中医药大学附属第一医院妇科门诊就诊的81例痰瘀互结型PCOS患者（高雄组53例，非高雄组28例）和55例对照组，分析和比较3组的临床生化各项指标。结果 3组间的临床特征比较：高雄组和非高雄组的多毛评分均高于对照组（P<0.05），高雄组的多毛评分高于非高雄组；高雄组和非高雄组的黑棘皮、痤疮、溢脂评分均显著高于对照组明显高于对照组（P<0.05）；3组间性激素水平的比较：高雄组LH、FSH、LH/FSH、T、AND、SHBG、FAI值高于对照组（P<0.05）；高雄组LH、LH/FSH、T、AND、FAI高于非高雄组（P<0.05）；非高雄组FSH、T、SHBG高于对照组（P<0.05）。3组间糖脂代谢水平的比较高雄组FINS、HOMA-IR、TC、HDL、LDL、ApoB、ApoB/ApoA值高于对照组（P<0.05）；高雄组TC、ApoB、ApoB/ApoA高于非高雄组（P<0.05）；非高雄组LDL、ApoB/ApoA高于对照组（P<0.05）。结论 痰瘀互结型PCOS患者其黑棘皮、痤疮、溢脂发生率较高；痰瘀互结型PCOS伴高雄激素血症患者具有较高的LH、LH/FSH，并易发生血脂代谢紊乱。 |
| 中文关键词:痰瘀互结型 多囊卵巢综合征 高雄激素血症 |
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| Clinical Features of Phlegm and Blood Stasis Mutual Junction Type Polycystic Ovary Syndrome with High Testosterone Levels |
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| Abstract:Objective Through comparing the features of phlegm and blood stasis mutual junction type PCOS with different testosterone levels to explore the clinical features. Methods Totally 81 PCOS patients were divided into HA group and non-HA group,55 healthy women served as contrals. Results Comparison of the clinical features among the three groups:hairy score is significantly higher in HA group;acanthosis nigricans,acne and excessive fat scores are significantly higher in HA group and non-HA group than control group. Comparison of sex hormone levels among three groups:LH, FSH, LH/FSH, T, AND, SHBG, FAI are higher in HA group and non-HA group than control group; LH, LH/FSH, T, AND, FAI is higher in HA group than non-HA group;FSH、T、SHBG is higher in non-HA group than control group. Comparison of sugar and lipid metabolism among three groups:FINS、HOMA-IR、TC、HDL、LDL、ApoB、ApoB/ApoA are higher in HA group and non-HA group than control group;TC、Apo-B、ApoB/ApoA are higher in HA group than non-HA group;LDL、ApoB/ApoA are higher in non-HA group than control group. Conclusion Phlegm and blood stasis mutual junction type PCOS have a higher incidence of acanthosis nigricans, acne and excessive fat; phlegm and blood stasis mutual junction type pcos with high testosterone levels have a higher level of LH and LH/FSH,and having a risk of blood lipid metabolic disorder. |
| keywords:Phlegm and blood stasis mutual junction Polycystic ovarian syndrome Hyperandrogenism |
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