冠心病与冠心病合并糖尿病患者临床用药规律分析
投稿时间:2016-08-08  修订日期:2016-09-02  点此下载全文
引用本文:李雪丽,邓冬,赵慧辉,陈静,王娟,王伟.冠心病与冠心病合并糖尿病患者临床用药规律分析[J].医学研究杂志,2017,46(4):44-48
DOI: 10.11969/j.issn.1673-548X.2017.04.012
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作者单位E-mail
李雪丽 100029 北京中医药大学  
邓冬 100029 北京中医药大学  
赵慧辉 100029 北京中医药大学  
陈静 100029 北京中医药大学  
王娟 100029 北京中医药大学  
王伟 100029 北京中医药大学 wangwei26960@126.com 
基金项目:国家自然科学基金资助项目(81302914)
中文摘要:目的 分析冠心病患者与冠心病合并糖尿病患者(以冠心病为第一诊断)的药物使用情况,探讨患病人群的年龄、性别特征,并比较二者的西药临床用药特点。方法 回顾首都医科大学附属北京安贞医院126例冠心病患者和86例冠心病合并糖尿病患者的具体信息,采用描述性统计(频数分布)和χ2检验等分析方法对这两类患者的性别和年龄分布规律、用药的药品频次和联合用药情况进行统计分析。结果 冠心病和冠心病合并糖尿病的患者主要以中老年为主。冠心病患者用药例次排序前4位为抗凝药、β受体阻断药、降脂药、硝酸酯类抗心绞痛药物;用药方式以五联用药为主。冠心病合并糖尿病患者用药例次排序前4位为抗凝药、降糖药、β受体阻断药、降脂药;用药方式以六联用药为主。结论 冠心病和冠心病合并糖尿病发病机制复杂,需要联合用药治疗。
中文关键词:冠心病  冠心病合并糖尿病  回顾性分析
 
Principle of Clinical Medication in Patients with Coronary Heart Disease and Coronary Heart Disease Complicated with Diabetes
Abstract:Objective To analyze the drugs utilization of patients with coronary heart disease and coronary heart disease complicated with diabetes (coronary heart disease is the first diagnosis). To discuss the characteristics of these patients in age and gender, comparing the western medicine used in clinic between the two groups. Methods We retrospectively investigated the information of 126 patients with coronary heart disease and 86 patients with coronary heart disease complicated with diabetes in Beijing Anzhen Hospital. Descriptive statistics frequency distribution and χ2 test were used to statistically analyze the distribution of gender and age, frequency of drugs usage and combined medication of the two groups. Results Patients are mainly aged people. We found that the top 4 drugs used by patients with coronary heart disease were successively anticoagulant drugs, β-adrenoceptor antagonist, lipid-lowering drugs and nitrates. Most of them received combination of five agents. We also found that the top 4 drugs used by patients with coronary heart disease complicated with diabetes were successively anticoagulant drugs,hypoglycemic agents, β-adrenoceptor antagonist and lipid- lowering drugs. Most of them received combination of six agents. Conclusion The pathogenesis of coronary heart disease and coronary heart disease complicated with diabetes is complex, therefore combination treatment is needed.
keywords:Coronary heart disease  Coronary heart disease complicated with diabetes  Retrospective analysis
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