| 1470nm激光汽化术与等离子双极电切术用于治疗良性前列腺增生的临床对比研究 |
| 投稿时间：2016-09-06 修订日期：2016-09-07 点此下载全文 |
| 引用本文：徐建,胡云飞,王潇.1470nm激光汽化术与等离子双极电切术用于治疗良性前列腺增生的临床对比研究[J].医学研究杂志,2017,46(4):123-127 |
| DOI：
10.11969/j.issn.1673-548X.2017.04.032 |
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| 中文摘要:目的 比较1470nm半导体激光前列腺汽化术（1470nm diode laser vaporization prostatectomy）与经尿道前列腺等离子双极电切术（bipolar transurethral plasmakinetic prostatectomy，TUPKP）用于治疗良性前列腺增生（benign prostatic hyperplasia，BPH）的临床治疗效果及安全性。方法 回顾性分析了笔者医院自2015年6月~2016年2月95例接受手术的BPH患者，按手术方式分为TUPKP组（52例）和 1470nm组（43例），分析比较患者的手术时间、术中出血量、术后留置导尿管时间、术后住院时间及评估手术疗效，包括术后1、3、6个月国际前列腺症状评分（International Prostate Symptom Score，IPSS）、生活质量评分（quality of life score，QoL）、最大尿流率（maximum urinary flow rate，Qmax）、残余尿量（Post-voided residual urine volume，PVR），并记录近期并发症。结果 两组患者术后IPSS评分、QoL评分、Qmax、PVR较术前均有显著改善，术后6个月IPSS评分：TUPKP组、1470组分别下降至6.3±2.6、6.7±2.4；术后6个月PVR： TUPKP组、1470组分别下降至23.1±20.9、24.3±19.9；术后6个月Qmax： TUPKP组、1470组分别升至18.5±3.1ml/s、18.7±2.8ml/s；两组手术疗效指标差异无统计学意义（P > 0.05）；手术时间方面TUPKP组、1470组分别为60.1±14.9min、69.3±12.9min（P < 0.05）， TUPKP组较1470nm组手术时间短。1470组在术后住院时间、留置尿管时间、术中出血量方面均优于TUPKP组（P < 0.05）。同时并发症方面，3组间差异无统计学意义（P > 0.05）。结论 两种手术方式对良性前列腺增生患者均有明确的临床疗效，但TUPKP组较1470组手术时间短，1470组较TUPKP组术中出血少、术后恢复快。 |
| 中文关键词:良性前列腺增生 经尿道等离子双极电切术 1470nm半导体激光 |
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| Clinical Comparative Study on 1470nm Diode Laser Vaporization Prostatectomy and Bipolar Transurethral Plasmakinetic Prostatectomy Used in the Treatment of Benign Prostatic Hyperplasia |
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| Abstract:Objective To compare the therapeutic effects of 1470nm diode laser vaporization prostatectomy and bipolar transurethral plasmakinetic prostatectomy (TUPKP) for treatment of benign prostatic hyperplasia (BPH). Methods From June 2015-February 2016 a total of 95 patients diagnosed with BPH were randomly divided into 2 group: 52 patients were treated with TUPKP while 43 patients with 1470 diode laser. All patients were followed up with mean operative time, intra-operative blood loss, postoperative hospital stay, postoperative catheterization time, postoperative complications, international prostate symptom score (IPSS), score of life quality (QoL),maximum flow rate (Qmax), post-void residual (PVR) before and after surgery. Results Compared with data of preoperation, postoperative IPSS, QoL, Qmax, PVR in 6 months revealed significant improvement in both of two groups. IPSS of TUPKP group and 1470 group respectively dropped to 6.3±2.6 and 6.7±2.4. In TUPKP group, PVR reduced to 23.1±20.9ml and in 1470 group decreased to 24.3±19.9ml. While Qmax increased to 18.5±3.1ml/s and 18.7±2.8ml/s respectively in TUPKP and 1470 group. In TUPKP group, operation time were 60.1±14.9min, significantly less than that in 1470 group of 69.3±12.9min (P < 0.05). Compared with catheterization time in 1470 group of 33.9±9.4h, the time in TUPKP group of 73.9±37.6h was shorter with significant difference (P < 0.05). While Curative effect of two groups of showed no significant difference (P > 0.05). Conclusion The clinical curative effect of two operation methods for patients with BPH showed no significant difference. 1470 group had longer operation time, while TUPKP group had less intraoperative bleeding and postoperative recovery. |
| keywords:Benign prostatic hyperplasia Bipolar transurethral plasmakinetic prostatectomy 1470nm diode laser |
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