| 子宫动脉栓塞术治疗子宫肌瘤的临床效果及对卵巢功能的影响 |
| 投稿时间：2016-09-29 修订日期：2016-10-07 点此下载全文 |
| 引用本文：朱晓玉,姚丽艳,孙业亮,赵雷.子宫动脉栓塞术治疗子宫肌瘤的临床效果及对卵巢功能的影响[J].医学研究杂志,2017,46(5):63-66 |
| DOI：
10.11969/j.issn.1673-548X.2017.05.017 |
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| 基金项目:新疆维吾尔自治区自然科学基金资助项目（2016D01C203）；乌鲁木齐市水磨沟区科学技术计划项目（201612） |
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| 中文摘要:目的 探讨子宫动脉栓塞术（UAE）治疗子宫肌瘤的临床效果其及对卵巢功能的影响。方法 收集2014年6月~2015年7月在笔者医院就诊的自愿接受子宫动脉栓塞治疗的子宫肌瘤患者50例，均在月经干净后3~7天内采用Seldinger技术进行股动脉穿刺，双侧子宫动脉经动脉造影证实后实施子宫动脉栓塞治疗。结果 50例患者均成功行子宫动脉栓塞术，有患者于术后1~3天均出现了不同程度地下腹痛、发热、少量阴道出血、排液等症状。持续4~6天后大多数可好转，所有患者均未出现严重并发症。所有患者于术后3、6、12个月分别行超声复查子宫与瘤体体积，术后随访患者血红蛋白、LH和HSH水平，多个时间点的重复测量资料首先采用重复测量方差分析，两两比较采用配对t检验，结果显示子宫与瘤体体积均缩小，随着UAE时间延长，子宫及瘤体体积均进行性缩小，差异有统计学意义（P<0.05）；UAE术后3、6、12个月血红蛋白水平均较术前有了不同程度的提高，差异有统计学意义（P<0.05）；UAE术前、术后3、6、12个月LH、FSH水平均无明显变化，UAE术前、术后差异无统计学意义（P>0.05）。结论 采用子宫动脉栓塞术治疗子宫肌瘤方法简单、创伤小、恢复快，并且术后对卵巢功能影响较小，是一种治疗子宫肌瘤全新的、安全有效的方法，临床上有广泛的应用前景。 |
| 中文关键词:子宫肌瘤 介入治疗 动脉栓塞 卵巢功能 |
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| Clinical Effect of Uterine Arterial Embolization in the Treatment of Uterine Fibroids and Its Influence on Ovarian Function |
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| Abstract:Objective To investigate the effect of uterine artery embolization in the treatment of uterine fibroids and its influence on ovarian function. Methods Collected 50 patients of uterine fibroids which were treated with uterine artery embolization in June 2014 to July 2015 in our hospital, in 3 to 7 days after menstruation clean seldinger technology is adopted to improve the femoral artery puncture, uterine artery embolization is proceed when bilateral uterine artery are confirmed by angiography. Results Uterine artery embolization was successfully performed in 50 patients, all patients appeared varying degrees of abdominal pain, fever, a small amount of vaginal bleeding, liquid discharge and other symptoms in postoperative 1-3days. Most can improve after 4-6days, no serious complications occurred. All of the patients do color doppler ultrasonography in the postoperative 3 months, 6 months and 12 months respectively to check tumors and uterus volume, to follow postoperative patients with hemoglobin, LH and FSH level. First of all, multiple time points of repeated measurement data use repetitive measure analysis of variance, then comparing two paired t-test, the results showed the uterus and tumors volume are shrinking as the UAE time extended, the difference was statistically significant (P<0.05), compared with preoperative hemoglobin level, the hemoglobin level of postoperative 3 months, 6 months and 12 months increased, the difference was statistically significant (P<0.05); The LH and FSH levels had no obvious change between preoperative and postoperative 3 months, 6 months and 12 months, there was no statistically significant difference (P>0.05). Conclusion The uterine artery embolization is simple, small trauma, rapid recovery, and its influence on ovarian function is small, is a new, safe and effective method in the treatment of uterine fibroids, have extensive application prospect in clinic. |
| keywords:Uterine fibroids Interventional therapy Artery embolization Ovarian function |
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