| 颈动脉粥样硬化与血浆肾素-血管紧张素水平的相关性 |
| 投稿时间：2016-09-18 修订日期：2016-10-08 点此下载全文 |
| 引用本文：周洲,童传凤,朱玉果.颈动脉粥样硬化与血浆肾素-血管紧张素水平的相关性[J].医学研究杂志,2017,46(5):115-118 |
| DOI：
10.11969/j.issn.1673-548X.2017.05.029 |
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| 中文摘要:目的 探讨高血压病患者颈动脉粥样硬化与血浆肾素-血管紧张素水平的关系。方法 对2015年1月~2016年3月在心血管内科住院的原发性高血压患者的临床资料进行回顾性研究。结果 颈动脉粥样硬化与年龄、血糖、总胆固醇、低密度脂蛋白、尿酸相关。血浆立卧位肾素-血管紧张素水平与颈动脉粥样硬化：随着立卧位血管紧张素Ⅱ水平、立位肾素水平的增高，颈动脉粥样硬化的发生率增高（P<0.05）。Logistic回归分析显示，年龄、卧位血管紧张素Ⅱ、总胆固醇、尿酸与颈动脉粥样硬化呈正相关，高密度胆固醇与颈动脉粥样硬化呈负相关（P<0.05）。结论 血浆血管紧张素Ⅱ水平与颈动脉粥样硬化呈独立相关关系。 |
| 中文关键词:颈动脉粥样硬化 肾素-血管紧张素系统 高血压 |
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| Association of Carotid Atherosclerosis and the Plasma Level of RAS |
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| Abstract:Objective To investigate the relationship of carotid artery atherosclerosis and the plasma level of RAS in hypertension patients. Methods We retrospectively analyzed clinic data of essential hypertension patients treated in the department of cardiology department between Jan 2015 and Mar 2016. Results Carotid artery plaque was associated with age, blood sugar, total cholesterol, low density lipoprotein-cholesterol, and uric acid. The prevalence of carotid artery atherosclerosis increased with increasing level of plasma erect and decubitus position angiotensin Ⅱ and erect position renin(P<0.05).Logistic regression analysis indicted that age, decubitus position angiotensin Ⅱ,TC, UA was positively associated with carotid atherosclerosis, HDL-C was negatively correlated with carotid atherosclerosis(P<0.05). Conclusion Carotid artery atherosclerosis is independently associated with AngⅡ. |
| keywords:Carotid artery atherosclerosis Renin-angiotensin system Hypertension |
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