| 超声引导下与徒手注射肉毒毒素治疗脑瘫患儿痉挛疗效比较 |
| 投稿时间：2016-10-31 修订日期：2016-11-18 点此下载全文 |
| 引用本文：向红卫,尹彦.超声引导下与徒手注射肉毒毒素治疗脑瘫患儿痉挛疗效比较[J].医学研究杂志,2017,46(7):168-170,180 |
| DOI：
10.11969/j.issn.1673-548X.2017.07.042 |
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| 中文摘要:目的 探讨超声引导下与徒手注射肉毒毒素对脑瘫患儿痉挛的疗效差别。方法 选取笔者医院2014年3月~2016年9月的98例脑瘫患儿进行注射肉毒毒素治疗，根据注射的方式不同分为超声引导组和徒手组各49例，分别进行超声指导引导注射肉毒毒素和徒手注射肉毒毒素，两组患儿的注射剂量均为3U/kg，采用改良Ashworth痉孪量表评定患儿治疗前后的肌痉孪程度，并采用粗大运动功能分级量表（GMFM量表评分）评价患儿治疗前后的运动能力，随访3个月，观察两组患儿的临床疗效。结果 超声引导组的总有效率（98.0%）明显高于徒手组（79.6%），差异有统计学意义（P<0.05）；两组患儿治疗前后的Ashworth评分和GMFM量表评分均明显得到改善，差异有统计学意义（P<0.05）；超声引导组的Ashworth评分和GMFM量表评分均明显优于徒手组，差异有统计学意义（P<0.05）。结论 注射肉毒毒素治疗脑瘫患儿可以有效的改善痉挛问题，采用超声引导下注射肉毒毒素治疗脑瘫患儿的疗效要好于徒手注射肉毒毒素。 |
| 中文关键词:脑瘫患儿 超声引导 徒手 肉毒毒素 临床疗效 |
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| Comparison of the Therapeutic Effect of Ultrasound Guided and Freehand Botulinum Toxin Type of the Treatment in Children with Cerebral Palsy |
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| Abstract:Objective To study the comparison of the therapeutic effect of Ultrasound guided and freehand botulinum toxin type of the treatment in children with cerebral palsy. Methods From March 2014 to September 2016, 98 cases of children with cerebral palsy in our hospital by injection of botulinum toxin were treated. According to the way of injection, the children were divided into ultrasound group and free group(n=49). They were respectively gave botulinum toxin injection by guided Ultrasound guided and freehand ultrasound injection of botulinum toxin injection. The amount of two groups of children was 3U/kg.Children muscle spasm degree of before and after treatment was assessed by modified Ashworth spasm scale. And exercise capacity of children before and after treatment was assessed by the gross motor function rating scale. The follow-up time was 3 months, the clinical curative effect of two groups of children was observed. Results The total efficiency of ultrasound guided group (98.0%) was significantly higher than the free group (79.6%), with statistically significant (P<0.05). Both groups before and after treatment in children with Ashworth score and GMFM score were significantly improved, with statistical significance (P<0.05). Ashworth score and GMFM scores of ultrasound guided group were significantly better than the free group, with statistically significant (P<0.05). Conclusion Botulinum toxin injection in the treatment of cerebral palsy children can effectively solve the spastic problem. Treatment of children with cerebral palsy by injecting botulinum toxin with ultrasound guided injection of botulinum toxin is better than manual injection of botulinum toxin. |
| keywords:Cerebral palsy children Ultrasound guided Unarmed Botulinum toxin Clinical efficacy |
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