| 心肌桥对桥前段冠状动脉粥样硬化的影响 |
| 投稿时间：2016-11-30 修订日期：2017-01-09 点此下载全文 |
| 引用本文：李玉明,陈伟彬,王星稳,李盖,周伟,张惠英.心肌桥对桥前段冠状动脉粥样硬化的影响[J].医学研究杂志,2017,46(9):75-79,83 |
| DOI：
10.11969/j.issn.1673-548X.2017.09.021 |
| 摘要点击次数: 1034 |
| 全文下载次数: 691 |
|
| 基金项目:河北省医学科学研究重点计划项目（20170927）；河北省唐山市科学技术研究与发展计划项目（14130270B） |
|
| 中文摘要:目的 探讨心肌桥对桥前段冠状动脉粥样硬化发生率及性质的影响。方法 回顾性分析465例经冠状动脉造影检查，图像质量符合诊断需要求并诊断为心肌桥-壁冠状动脉患者影像资料，另随机选取1806例同时期经冠状动脉造影检查未检出心肌桥-壁冠状动脉患者的影像资料作为对照组，比较两组患者桥前段粥样硬化发生率差异。两组患者临床资料（年龄、性别、高血压、高脂血、糖尿病及吸烟情况）比较差异无统计学意义。根据斑块测得的CT值（HU）分类斑块性质为钙化斑块（CT值约196~817HU）、非钙化斑块（CT值约-12~47HU）及混合斑块（两种成分均有）组，比较心肌桥对桥前段冠状动脉粥样硬化斑块性质的影响。结果 465例心肌桥患者中，发现粥样硬化299例（64.30%，299/465），而对照组中发现粥样硬化569例（31.51%，569/1806），桥前段动脉粥样硬化发生率远高于对照组，差异有统计学意义（P < 0.05）。发现心肌桥并患有粥样硬化的患者中，钙化斑块93例（31.10%，93/299），非钙化斑块95例（31.77%，95/299），混合斑块111例（37.12%，111/299）；对照组中，钙化斑块235例（41.30%，235/569），非钙化斑块92例（16.17%，92/569），混合斑块242例（42.53%，242/569），两组比较显示载心肌桥（myocardial bridge，MB）患者的非钙化斑块的发生率明显增加，差异有统计学意义（P < 0.05）。结论 心肌桥-壁冠状动脉（MB-MCA）会增加桥前段冠状动脉粥样硬化发生的概率，且3种斑块比较，明显增加了非钙化斑块的发生率。 |
| 中文关键词:多层螺旋CT 心肌桥-壁冠状动脉 粥样硬化 斑块性质 |
| |
| Investigate the Effect of Myocardial Bridge on Coronary Artery Atherosclerosis in the Anterior Segment of the Bridge |
|
|
| Abstract:Objective To investigate the effect of myocardial bridge on the incidence and characteristics of coronary atherosclerosis in the anterior segment of the bridge. Methods A total of 465 cases of coronary angiography, image quality and diagnosis requires the diagnosis of myocardial bridge mural coronary artery imaging data were retrospectivedly analysed.And another randomly selected 1806 cases of the same period were not detected by coronary angiography imaging data of mural coronary artery in patients with myocardial bridge as control group, comparing two groups of patients with bridge some differences in the incidence of atherosclerosis. Clinical data (age, sex, hypertension, diabetes, hyperlipidemia, smoking) were not statistically significant between the two groups. According to the measured value of CT plaque (HU) classification of plaque calcified plaques (CT=196-817HU), non calcified the control group plaque (CT value of about -12-47HU), mixed plaque (two components were) group, we compared the effects of myocardial bridge on coronary artery plaque of the front bridge. Results From 465 patients with myocardial bridge,we found atherosclerosis in 299 cases (64.30%, 299/465), while in 569 cases (31.51%, 569/1806)from the control group.The front bridge rate of atherosclerosis is much higher than that of the control group, which was statistically significant different (P<0.05). Among the patients which were found and diagnosed with myocardial bridge atherosclerosis,there were 93 cases of calcified plaque(31.10%, 93/299), 95 cases of non calcified plaque(31.77%, 95/299), 111 cases of mixed plaque (37.12%, 111/299); while among the control group there were 235 cases of calcified plaque (41.30%, 235/569),92 cases of non calcified plaque (16.17%, 92/569), 242 cases of mixed plaque (42.53%, 242/569), Comparation of the two groups showed the incidence of non calcified plaque load in MB patients significantly increases, which was statistically significant difference (P< 0.05). Conclusion Myocardial bridge mural coronary artery (MB-MCA) can increase the probability of coronary atherosclerosis in the anterior segment of the bridge, and the incidence of non calcified plaque is significantly increased compared with the three types of plaque. |
| keywords:Multislice spiral CT Myocardial bridge-wall coronary artery Atherosclerosis Plaque properties |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
